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SOCS2 抗体 (AA 96-198)

This anti-SOCS2 antibody is a 兔 多克隆 antibody detecting SOCS2 in WB. Suitable for 人 和 大鼠.
产品编号 ABIN3042487
发货至: 中国
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Quick Overview for SOCS2 抗体 (AA 96-198) (ABIN3042487)

抗原

See all SOCS2 抗体
SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))

适用

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人, 大鼠

宿主

  • 53
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克隆类型

  • 34
  • 22
多克隆

标记

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This SOCS2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

    • 8
    • 3
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    AA 96-198

    原理

    Anti-SOCS2 Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-SOCS2 Antibody (ABIN3042487). Tested in WB applications. This antibody reacts with Human, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human SOCS2 recombinant protein (Position: R96-V198). Human SOCS2 shares 96.1% and 95.1% amino acid (aa) sequence identity with mouse and rat SOCS2, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Rat

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))

    别名

    SOCS2

    背景

    Synonyms: Suppressor of cytokine signaling 2,SOCS-2,Cytokine-inducible SH2 protein 2,CIS-2,STAT-induced STAT inhibitor 2,SSI-2,SOCS2,CIS2, SSI2, STATI2,

    Tissue Specificity: High expression in heart, placenta, lung, kidney and prostate.

    Background: Suppressor of cytokine signaling 2 is a protein that in humans is encoded by the SOCS2 gene. This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signalling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10 and interferon-gamma (IFN-gamma). The protein encoded by this gene is found to interact with the cytoplasmic domain of insulin-like growth factor 1 receptor (IGF1R), and thus is thought to be involved in the regulation of IGF1R mediated cell signaling. By cytogenetic and radiation hybrid mapping, Yandava et al. (1999) mapped the SOCS2 gene to chromosome 12q21.3-q23.

    Sequence Similarities: Contains 1 SH2 domain.

    分子量

    22 kDa

    基因ID

    8835

    UniProt

    O14508

    途径

    JAK/STAT Signaling, Response to Growth Hormone Stimulus
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