SOCS2 抗体 (AA 96-198)
Quick Overview for SOCS2 抗体 (AA 96-198) (ABIN3042487)
抗原
See all SOCS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 96-198
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原理
- Anti-SOCS2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SOCS2 Antibody Picoband® (ABIN3042487). Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SOCS2 recombinant protein (Position: R96-V198). Human SOCS2 shares 96.1% and 95.1% amino acid (aa) sequence identity with mouse and rat SOCS2, respectively.
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亚型
- IgG
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anti-Suppressor of Cytokine Signaling 2 (SOCS2) (AA 1-198) antibody
SOCS2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 2 (SOCS2) antibodySOCS2 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Suppressor of Cytokine Signaling 2 (SOCS2) antibodySOCS2 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 2 (SOCS2) (AA 1-198) antibodySOCS2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 2 (SOCS2) (AA 99-198) antibodySOCS2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 2 (SOCS2) (AA 1-198) antibodySOCS2 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 2 (SOCS2) (AA 1-198) antibodySOCS2 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 2 (SOCS2) antibodySOCS2 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 2 (SOCS2) (AA 99-198) antibodySOCS2 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3E7 unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Rat
1. "Entrez Gene: SOCS2 suppressor of cytokine signaling 2". 2. Dey BR, Spence SL, Nissley P, Furlanetto RW (September 1998). "Interaction of human suppressor of cytokine signaling (SOCS)-2 with the insulin-like growth factor-I receptor". J. Biol. Chem. 273 (37): 24095-101. 3. Greenhalgh CJ, Bertolino P, Asa SL, Metcalf D, Corbin JE, Adams TE, Davey HW, Nicola NA, Hilton DJ, Alexander WS (June 2002). "Growth enhancement in suppressor of cytokine signaling 2 (SOCS-2)-deficient mice is dependent on signal transducer and activator of transcription 5b (STAT5b)". Mol. Endocrinol. 16 (6): 1394-406. 4. Masuhara M, Sakamoto H, Matsumoto A, Suzuki R, Yasukawa H, Mitsui K, Wakioka T, Tanimura S, Sasaki A, Misawa H, Yokouchi M, Ohtsubo M, Yoshimura A (Nov 1997). "Cloning and characterization of novel CIS family genes". Biochem Biophys Res Commun 239 (2): 439-46. 5. Minamoto S, Ikegame K, Ueno K, Narazaki M, Naka T, Yamamoto H, Matsumoto T, Saito H, Hosoe S, Kishimoto T (Sep 1997). "Cloning and functional analysis of new members of STAT induced STAT inhibitor (SSI) family: SSI-2 and SSI-3". Biochem Biophys Res Commun 237 (1): 79-83. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))
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别名
- SOCS2
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背景
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Synonyms: Suppressor of cytokine signaling 2,SOCS-2,Cytokine-inducible SH2 protein 2,CIS-2,STAT-induced STAT inhibitor 2,SSI-2,SOCS2,CIS2, SSI2, STATI2,
Tissue Specificity: High expression in heart, placenta, lung, kidney and prostate.
Background: Suppressor of cytokine signaling 2 is a protein that in humans is encoded by the SOCS2 gene. This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signalling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10 and interferon-gamma (IFN-gamma). The protein encoded by this gene is found to interact with the cytoplasmic domain of insulin-like growth factor 1 receptor (IGF1R), and thus is thought to be involved in the regulation of IGF1R mediated cell signaling. By cytogenetic and radiation hybrid mapping, Yandava et al. (1999) mapped the SOCS2 gene to chromosome 12q21.3-q23.
Sequence Similarities: Contains 1 SH2 domain.
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分子量
- 22 kDa
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基因ID
- 8835
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UniProt
- O14508
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途径
- JAK/STAT Signaling, Response to Growth Hormone Stimulus
抗原
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