KLF6 抗体 (AA 38-205)
Quick Overview for KLF6 抗体 (AA 38-205) (ABIN3042475)
抗原
See all KLF6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 38-205
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原理
- Anti-KLF6 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-KLF6 Antibody Picoband® (ABIN3042475). Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human KLF6 recombinant protein (Position: E38-N205). Human KLF6 shares 92% and 90% amino acid (aa) sequences identity with mouse and rat KLF6, respectively.
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亚型
- IgG
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anti-Kruppel-Like Factor 6 (KLF6) (AA 1-260) antibody
KLF6 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A9 unconjugated
anti-Kruppel-Like Factor 6 (KLF6) (AA 71-283) antibodyKLF6 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4C7D6 unconjugated
anti-Kruppel-Like Factor 6 (KLF6) (AA 155-204) antibodyKLF6 适用: 人, 大鼠, 犬, 马, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Kruppel-Like Factor 6 (KLF6) (AA 1-100) antibodyKLF6 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 3C4 unconjugated
anti-Kruppel-Like Factor 6 (KLF6) (AA 40-200) antibodyKLF6 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Kruppel-Like Factor 6 (KLF6) antibodyKLF6 适用: 人, 小鼠 WB, IHC, FACS, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-Kruppel-Like Factor 6 (KLF6) (AA 159-186), (C-Term) antibodyKLF6 适用: 人, 小鼠 WB, FACS, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Kruppel-Like Factor 6 (KLF6) antibodyKLF6 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Kruppel-Like Factor 6 (KLF6) antibodyKLF6 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Kruppel-Like Factor 6 (KLF6) antibodyKLF6 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Rat
1. Onyango P, Koritschoner NP, Patrito LC, Zenke M, Weith A (Apr 1998). "Assignment of the gene encoding the core promoter element binding protein (COPEB) to human chromosome 10p15 by somatic hybrid analysis and fluorescence in situ hybridization". Genomics 48 (1): 143-4. 2. Li D, Yea S, Dolios G et al. (October 2005). "Regulation of Kruppel-like factor 6 tumor suppressor activity by acetylation". Cancer Res. 65 (20): 9216-25. 3. "Entrez Gene: KLF6 Kruppel-like factor 6" -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- KLF6 (Kruppel-Like Factor 6 (KLF6))
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别名
- KLF6
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背景
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Synonyms: Krueppel-like factor 6,B-cell-derived protein 1,Core promoter element-binding protein,GC-rich sites-binding factor GBF,Proto-oncogene BCD1,Suppressor of tumorigenicity 12 protein,Transcription factor Zf9,KLF6,BCD1, COPEB, CPBP, ST12,
Tissue Specificity: Highly expressed in placenta followed by spleen, thymus, prostate, testis, small intestine and colon. Weakly expressed in pancreas, lung, liver, heart and skeletal muscle. Also expressed in fetal brain, spleen and thymus.
Background: Krueppel-like factor 6 (KLF6) is a protein that in humans is encoded by the KLF6 gene. It is a tumor suppressor gene which is located on 10p15.1. This gene encodes a nuclear protein that has three zinc fingers at the end of its C-terminal domain, a serine/threonine-rich central region, and an acidic domain lying within the N-terminal region. The zinc fingers of this protein are responsible for the specific DNA binding with the guanine-rich core promoter elements. The central region might be involved in activation or posttranslational regulatory pathways, and the acidic N-terminal domain might play an important role in the process of transcriptional activation. It is capable of activating transcription approximately 4-fold either on homologous or heterologous promoters. The DNA binding and transcriptional activity of this protein, in conjunction with its expression pattern, suggests that this protein may participate in the regulation and/or maintenance of the basal expression of pregnancy-specific glycoprotein genes and possibly other TATA box-less genes.
Sequence Similarities: Belongs to the krueppel C2H2-type zinc-finger protein family.
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分子量
- 37 kDa
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基因ID
- 1316
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UniProt
- Q99612
抗原
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