KIN 抗体 (AA 3-202)
Quick Overview for KIN 抗体 (AA 3-202) (ABIN3042474)
抗原
See all KIN 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 3-202
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原理
- Anti-KIN Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-KIN Antibody Picoband® (ABIN3042474). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human KIN recombinant protein (Position: K3-K202). Human KIN shares 98% amino acid (aa) sequence identity with mouse KIN.
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亚型
- IgG
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anti-KIN, Antigenic Determinant of RecA Protein Homolog (KIN) (AA 230-279) antibody
KIN 适用: 人, Cow, 犬, 豚鼠, 马, 兔 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-KIN, Antigenic Determinant of RecA Protein Homolog (KIN) (Middle Region) antibodyKIN 适用: 人, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-KIN, Antigenic Determinant of RecA Protein Homolog (KIN) (AA 166-215) antibodyKIN 适用: 人, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 猴, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-KIN, Antigenic Determinant of RecA Protein Homolog (KIN) (AA 180-270) antibodyKIN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-KIN, Antigenic Determinant of RecA Protein Homolog (KIN) (N-Term) antibodyKIN 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-KIN, Antigenic Determinant of RecA Protein Homolog (KIN) (AA 48-64), (N-Term) antibodyKIN 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
1. Kannouche, P., Mauffrey, P., Pinon-Lataillade, G., Mattei, M. G., Sarasin, A., Daya-Grosjean, L., Angulo, J. F. Molecular cloning and characterization of the human KIN17 cDNA encoding a component of the UVC response that is conserved among metazoans. Carcinogenesis 21: 1701-1710, 2000. 2. Timchenko, T., Bailone, A., Devoret, R. Btcd, a mouse protein that binds to curved DNA, can substitute in Escherichia coli for H-NS, a bacterial nucleoid protein. EMBO J. 15: 3986-3992, 1996. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- KIN (KIN, Antigenic Determinant of RecA Protein Homolog (KIN))
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别名
- KIN
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背景
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Synonyms: DNA/RNA-binding protein KIN17,Binding to curved DNA,KIN, antigenic determinant of recA protein homolog,KIN ,BTCD, KIN17,
Tissue Specificity: Ubiquitously expressed in all tissues examined, with highest levels in skeletal muscle, heart and testis. Differentially expressed in non-tumorigenic and tumorigenic cell lines. Highly expressed in proliferating epithelial keratinocyte cells in vitro (at protein level). .
Background: DNA/RNA-binding protein KIN17, also known as BTCD or KIN17, is a protein that in humans is encoded by the KIN gene. This gene is mapped to 10p14. The protein encoded by this gene is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. Short-wave ultraviolet light provokes the relocalization of the protein, suggesting its participation in the cellular response to DNA damage. Originally selected based on protein-binding with RecA antibodies, the mouse protein presents a limited similarity with a functional domain of the bacterial RecA protein, a characteristic shared by this human ortholog. Alternative splicing of this gene results in multiple transcript variants.
Sequence Similarities: Belongs to the KIN17 family.
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分子量
- 45 kDa
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基因ID
- 22944
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UniProt
- O60870
抗原
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