KAT2A 抗体 (N-Term)
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Quick Overview for KAT2A 抗体 (N-Term) (ABIN3042472)
抗原
See all KAT2A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 75-106, N-Term
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原理
- Anti-KAT2A/GCN5 Antibody
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序列
- DPARPGLSQQ QRASQRKAQV RGLPRAKKLE KL
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-KAT2A/GCN5 Antibody (ABIN3042472). Tested in WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human KAT2A/GCN5, identical to the related mouse and rat sequences.
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- KAT2A (K(lysine) Acetyltransferase 2A (KAT2A))
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别名
- KAT2A
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背景
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Synonyms: Histone acetyltransferase KAT2A,2.3.1.48,General control of amino acid synthesis protein 5-like 2,Histone acetyltransferase GCN5,HsGCN5,Lysine acetyltransferase 2A,STAF97,KAT2A,GCN5, GCN5L2, HGCN5,
Tissue Specificity: Expressed in all tissues tested, with most abundant expression in ovary.
Background: Histone acetyltransferase KAT2A?is an?enzyme?that in humans is encoded by the?KAT2A?gene. It is mapped to 17q21. KAT2A, or GCN5, GCN5L2, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. The GCN5 protein, a regulator of transcription activation in yeast, promotes maximal levels of transcription by 2 transcriptional activators, GCN4 and the HAP2-HAP3-HAP4 complex.?The GCN4 protein activates transcription of a large number of amino acid biosynthetic genes under limiting amino acid conditions and the HAP2-HAP3-HAP4 complex is thought to mediate transcription of genes involved in respiratory functions.?GCN5 also functions as a repressor of NF-kappa-B by promoting ubiquitination of the NF-kappa-B subunit RELA in a HAT-independent manner.
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分子量
- 94 kDa
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基因ID
- 2648
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UniProt
- Q92830
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途径
- Chromatin Binding, Tube Formation
抗原
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