HSPG2 抗体 (AA 524-701)
Quick Overview for HSPG2 抗体 (AA 524-701) (ABIN3042466)
抗原
See all HSPG2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 524-701
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原理
- Anti-Heparan Sulfate Proteoglycan 2/HSPG2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Heparan Sulfate Proteoglycan 2/HSPG2 Antibody Picoband® (ABIN3042466). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human HSPG2 recombinant protein (Position: F524-K701). Human HSPG2 shares 86% amino acid (aa) sequence identity with mouse HSPG2.
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亚型
- IgG
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anti-Heparan Sulfate Proteoglycan 2 (HSPG2) (AA 4149-4391) antibody
HSPG2 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Heparan Sulfate Proteoglycan 2 (HSPG2) antibodyHSPG2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Heparan Sulfate Proteoglycan 2 (HSPG2) antibodyHSPG2 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Heparan Sulfate Proteoglycan 2 (HSPG2) antibodyHSPG2 适用: 人, 小鼠, Cow, 鱼, 猴, Pig IHC, IF, FACS, ISt, StM 宿主: 大鼠 Monoclonal A7L6 unconjugated
anti-Heparan Sulfate Proteoglycan 2 (HSPG2) antibodyHSPG2 适用: 人, Cow WB, IHC, ELISA, IP, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal A71 unconjugated
anti-Heparan Sulfate Proteoglycan 2 (HSPG2) antibodyHSPG2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Heparan Sulfate Proteoglycan 2 (HSPG2) (AA 25-134) antibodyHSPG2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human
1. Arikawa-Hirasawa E, Le AH, Nishino I, Nonaka I, Ho NC, Francomano CA et al. (May 2002). 2. Iozzo RV (1994). "Perlecan: a gem of a proteoglycan". Matrix Biol. 14 (3): 203-8. 3. Kallunki P, Eddy RL, Byers MG, Kestilä M, Shows TB, Tryggvason K (October 1991). "Cloning of human heparan sulfate proteoglycan core protein, assignment of the gene (HSPG2) to 1p36.1----p35 and identification of a BamHI restriction fragment length polymorphism". Genomics 11 (2): 389-96. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- HSPG2 (Heparan Sulfate Proteoglycan 2 (HSPG2))
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别名
- HSPG2
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背景
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Synonyms: Basement membrane-specific heparan sulfate proteoglycan core protein,HSPG,Perlecan,PLC,Endorepellin,LG3 peptide,HSPG2,
Tissue Specificity: Found in the basement membranes.
Background: Perlecan (PLC) also known as HSPG2, is a protein that in humans is encoded by the HSPG2 gene. It is mapped to 1p36.12. Perlecan is highly conserved across species and the available data indicate that it has evolved from ancient ancestors by gene duplication and exonshuffling. Perlecan is a key component of the vascular extracellular matrix, here it interacts with a variety of other matrix components and helps to maintain the endothelial barrier function. It is a potent inhibitor of smooth muscle cell proliferation and is thus thought to help maintain vascular homeostasis. Perlecan can also promote growth factor (e.g., FGF2) activity and thus stimulate endothelial growth and re-generation.
Sequence Similarities: Contains 4 EGF-like domains.
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分子量
- 469 kDa
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基因ID
- 3339
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UniProt
- P98160
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途径
- Glycosaminoglycan Metabolic Process, Lipid Metabolism
抗原
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