HRG 抗体 (AA 19-200)
Quick Overview for HRG 抗体 (AA 19-200) (ABIN3042459)
抗原
See all HRG 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 19-200
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原理
- Anti-HRG Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-HRG Antibody Picoband® (ABIN3042459). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human HRG recombinant protein (Position: V19-V200). Human HRG shares 71% and 69% amino acid (aa) sequences identity with mouse and rat HRG, respectively.
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亚型
- IgG
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anti-Histidine-Rich Glycoprotein (HRG) (AA 19-525) antibody
HRG 适用: 大鼠 WB, IHC 宿主: 小鼠 Monoclonal C3 unconjugated
anti-Histidine-Rich Glycoprotein (HRG) (AA 18-254) antibodyHRG 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histidine-Rich Glycoprotein (HRG) (AA 106-302) antibodyHRG 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histidine-Rich Glycoprotein (HRG) (AA 93-328) antibodyHRG 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histidine-Rich Glycoprotein (HRG) (AA 18-254) antibodyHRG 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D2 unconjugated
anti-Histidine-Rich Glycoprotein (HRG) (AA 412-511) antibodyHRG 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Histidine-Rich Glycoprotein (HRG) antibodyHRG 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Histidine-Rich Glycoprotein (HRG) (AA 1-525) antibodyHRG 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Histidine-Rich Glycoprotein (HRG) (AA 1-525) antibodyHRG 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Histidine-Rich Glycoprotein (HRG) (C-Term) antibodyHRG 适用: 人, 兔 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human
1. Hennis BC, Kluft C (Sep 1991). "KpnI RFLP in the human histidine-rich glycoprotein gene". Nucleic Acids Res 19 (15): 4311-4311. 2. "Entrez Gene: HRG histidine-rich glycoprotein" 3. Poon IK, Patel KK, Davis DS, Parish CR, Hulett MD (2011). "Histidine-rich glycoprotein: the Swiss Army knife of mammalian plasma". Blood 117 (7): 2093-101. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- HRG (Histidine-Rich Glycoprotein (HRG))
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别名
- HRG
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背景
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Synonyms: Histidine-rich glycoprotein,Histidine-proline-rich glycoprotein,HPRG,HRG,
Tissue Specificity: Expressed in macrophages and in malignant cells. Expressed by the liver and secreted in plasma (at protein level). .
Background: Histidine-rich glycoprotein (HRG) is a protein that in humans is encoded by the HRG gene. It is mapped to 3q27.3. HRG contains two cystatin-like domains and is located in plasma and platelets. The protein can bind heme, dyes and divalent metal ions. It also can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels. HRG is thought to have multiple roles as a protein in the human blood, including roles in immunity, angiogenesis and coagulation.
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分子量
- 60 kDa
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基因ID
- 3273
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UniProt
- P04196
抗原
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