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HPSE 抗体 (Middle Region)

Name: HPSE 抗体 (Middle Region)
SKU: ABIN3042457
Availability: OutOfStock

This anti-HPSE antibody is a 兔多克隆 antibody detecting HPSE in WB. Suitable for 人和大鼠. This Primary Antibody has been cited in 3+ publications.

Anti- Heparanase 1 Picoband antibody, Western blotting All lanes: Anti Heparanase 1 at 0. (HPSE 抗体 (Middle Region))

1 image

(3 references)

产品编号 ABIN3042457

发货至: 中国

Quick Overview for HPSE 抗体 (Middle Region) (ABIN3042457)

抗原

See all HPSE 抗体

HPSE (Heparanase (HPSE))

适用

人, 大鼠

宿主

兔

克隆类型

多克隆

标记

This HPSE antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product HPSE Primary Antibody

抗原表位
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1
AA 301-331, Middle Region

原理

Anti-Heparanase 1/HPSE Antibody

序列

NGRTATKEDF LNPDVLDIFI SSVQKVFQVV E

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-Heparanase 1/HPSE Antibody (ABIN3042457). Tested in WB applications. This antibody reacts with Human, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence in the middle region of human Heparanase 1, different from the related mouse and rat sequences by eight amino acids.

亚型

IgG
anti-Heparanase (HPSE) (AA 34-115) antibody
HPSE 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Heparanase (HPSE) (AA 353-464) antibody
HPSE 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Heparanase (HPSE) (AA 40-188) antibody
HPSE 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Heparanase (HPSE) (AA 280-412) antibody
HPSE 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Heparanase (HPSE) (AA 400-543) antibody
HPSE 适用: 人 WB, ICC, IF 宿主: 小鼠 Monoclonal C1 unconjugated

anti-Heparanase (HPSE) (AA 36-275) antibody
HPSE 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Heparanase (HPSE) (AA 68-117) antibody
HPSE 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Heparanase (HPSE) antibody
HPSE 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Heparanase (HPSE) (AA 263-523) antibody
HPSE 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Heparanase (HPSE) (AA 72-170) antibody
HPSE 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D7 unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human, Rat

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Tang, Piao, Zhao, Mu, Li, Ma, Song, Wang, Zhao, Zhang: "Expression and correlation of matrix metalloproteinase-9 and heparanase in patients with breast cancer." in: Medical oncology (Northwood, London, England), Vol. 31, Issue 7, pp. 26, (2014) (PubMed).

Huining, Yi, Dihong, Yifeng, Man, Ting, Jingting: "Inhibition of choriocarcinoma by Fe3O4-dextran-anti-β-human chorionic gonadotropin nanoparticles containing antisense oligodeoxynucleotide of heparanase." in: International journal of nanomedicine, Vol. 8, pp. 4371-8, (2014) (PubMed).

Tang, Zhang, Zhao, Wang, Lu, Song, Zhao, Kang, Wang, Xu, Tian: "The expression and clinical significance of microRNA-1258 and heparanase in human breast cancer." in: Clinical biochemistry, Vol. 46, Issue 10-11, pp. 926-32, (2013) (PubMed).
抗原

HPSE (Heparanase (HPSE))

别名

HPSE

背景

Synonyms: Heparanase,3.2.1.166,Endo-glucoronidase,Heparanase-1,Hpa1,Heparanase 8 kDa subunit,Heparanase 50 kDa subunit,HPSE,HEP, HPA, HPA1, HPR1, HPSE1, HSE1,
Tissue Specificity: Highly expressed in placenta and spleen and weakly expressed in lymph node, thymus, peripheral blood leukocytes, bone marrow, endothelial cells, fetal liver and tumor tissues. Also expressed in hair follicles, specifically in both Henle's and Huxley's layers of inner the root sheath (IRS) at anagen phase. .
Background: Heparanase, also known as HPSE, is an enzyme that acts both at the cell-surface and within the extracellular matrix to degrade polymeric heparan sulfate molecules into shorter chain length oligosaccharides. Heparanase is an endo-beta-D-glucuronidase capable of cleaving heparan sulfate and has been implicated in inflammation and tumor angiogenesis and metastasis. The successful penetration of the endothelial cell layer that lines the interior surface of blood vessels is an important process in the formation of blood borne tumour metastases. Heparan sulfate proteoglycans are major constituents of this layer and it has been shown that increased metastatic potential corresponds with increased heparanase activity for a number of cell lines.
Sequence Similarities: Belongs to the cyclin family. Cyclin AB subfamily.

分子量

61 kDa

基因ID

10855

UniProt

Q9Y251

途径

Glycosaminoglycan Metabolic Process