HNF1B 抗体 (C-Term)
Quick Overview for HNF1B 抗体 (C-Term) (ABIN3042452)
抗原
See all HNF1B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 496-525, C-Term
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原理
- Anti-HNF1 beta/HNF1B Antibody Picoband®
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序列
- AQQPFMAAVT QLQNSHMYAH KQEPPQYSHT
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-HNF1 beta/HNF1B Antibody Picoband® (ABIN3042452). Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human HNF1 beta, identical to the related mouse and rat sequences.
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亚型
- IgG
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anti-HNF1 Homeobox B (HNF1B) (AA 29-118) antibody
HNF1B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E9 unconjugated
anti-HNF1 Homeobox B (HNF1B) (AA 29-118) antibodyHNF1B 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3H4 unconjugated
anti-HNF1 Homeobox B (HNF1B) (N-Term) antibodyHNF1B 适用: 人, 大鼠, 小鼠, 斑马鱼, 犬, Cow, 马, 豚鼠, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-HNF1 Homeobox B (HNF1B) (AA 159-300) antibodyHNF1B 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-HNF1 Homeobox B (HNF1B) (AA 1-557) antibodyHNF1B 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-HNF1 Homeobox B (HNF1B) (AA 539-704) antibodyHNF1B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-HNF1 Homeobox B (HNF1B) (Internal Region) antibodyVerified HNF1B 适用: 人, 小鼠 WB, ELISA, ICC 宿主: 山羊 Polyclonal unconjugated
anti-HNF1 Homeobox B (HNF1B) (Internal Region) antibodyHNF1B 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-HNF1 Homeobox B (HNF1B) (AA 100-200) antibodyHNF1B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-HNF1 Homeobox B (HNF1B) (C-Term) antibodyHNF1B 适用: 人, 大鼠, 小鼠, 犬, Cow, 马, 豚鼠, 兔, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Rat
1. Bach, I., Mattei, M.-G., Cereghini, S., Yaniv, M. Two members of an HNF1 homeoprotein family are expressed in human liver. Nucleic Acids Res. 19: 3553-3559, 1991. 2. "Entrez Gene: TCF2 transcription factor 2, hepatic, LF-B3, variant hepatic nuclear factor". 3. Verdeguer, F., Le Corre, S., Fischer, E., Callens, C., Garbay, S., Doyen, A., Igarashi, P., Terzi, F., Pontoglio, M. A mitotic transcriptional switch in polycystic kidney disease. (Letter) Nature Med. 16: 106-110, 2010. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- HNF1B (HNF1 Homeobox B (HNF1B))
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别名
- HNF1B
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背景
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Synonyms: Hepatocyte nuclear factor 1-beta,HNF-1-beta,HNF-1B,Homeoprotein LFB3,Transcription factor 2,TCF-2,Variant hepatic nuclear factor 1,vHNF1,HNF1B,TCF2,
Tissue Specificity: Expressed in adult heart, placenta, lung, kidney, pancreas, prostate, and ovary and in fetal lung and kidney.
Background: HNF1 homeobox B (hepatocyte nuclear factor 1 homeobox B), also known as HNF1B or transcription factor 2 (TCF2), is a human gene. It is a member of the homeodomain-containing superfamily of transcription factors. This gene is mapped to 17q12. The HNF1B protein is believed to form heterodimers with another liver-specific member of this transcription factor family, TCF1. HNF1B functions as both a classic transcriptional activator and as a bookmarking factor that marks target genes for rapid transcriptional reactivation after mitosis. HNF1B also can regulate renal tubulogenesis by controlling expression of SOC3. Mutation of HNF1B that disrupts normal function has been identified as the cause of MODY5 (Maturity-Onset of Diabetes, Type 5).
Sequence Similarities: Belongs to the HNF1 homeobox family.
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分子量
- 61 kDa
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基因ID
- 6928
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UniProt
- P35680
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途径
- Hormone Transport, Stem Cell Maintenance, Tube Formation
抗原
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