HNF1A 抗体 (AA 431-631)
(1 reference)Quick Overview for HNF1A 抗体 (AA 431-631) (ABIN3042451)
抗原
See all HNF1A 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 431-631
-
原理
- Anti-HNF1/HNF1A Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins
-
产品特性
- Anti-HNF1/HNF1A Antibody Picoband® (ABIN3042451). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human HNF1 recombinant protein (Position: A431-Q631). Human HNF1 shares 93% and 92% amino acid (aa) sequences identity with mouse and rat HNF1, respectively.
-
亚型
- IgG
-
-
anti-HNF1 Homeobox A (HNF1A) antibody
HNF1A 适用: 人 WB, IHC (p), IP, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-HNF1 Homeobox A (HNF1A) (AA 214-339) antibodyHNF1A 适用: 人 ELISA, IHC, Coat, StM 宿主: 小鼠 Monoclonal HNF1A-2087 unconjugated
anti-HNF1 Homeobox A (HNF1A) (AA 179-228) antibodyHNF1A 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, Pig, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-HNF1 Homeobox A (HNF1A) (AA 532-631) antibodyHNF1A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6G4 unconjugated
anti-HNF1 Homeobox A (HNF1A) (N-Term) antibodyHNF1A 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-HNF1 Homeobox A (HNF1A) (Internal Region) antibodyVerified HNF1A 适用: 人 ELISA, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-HNF1 Homeobox A (HNF1A) (N-Term) antibodyHNF1A 适用: 人, 小鼠, 大鼠, Pig, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-HNF1 Homeobox A (HNF1A) (AA 177-205) antibodyHNF1A 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-HNF1 Homeobox A (HNF1A) (AA 201-350) antibodyHNF1A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-HNF1 Homeobox A (HNF1A) (AA 179-228) antibodyHNF1A 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, Cow, Pig, Bat, 绵羊, 斑马鱼, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.1-0.5 μg/mL, Human
1. Courtois, G., Morgan, J. G., Campbell, L. A., Fourel, G., Crabtree, G. R. Interaction of a liver-specific nuclear factor with the fibrinogen and alpha-1-antitrypsin promoters. Science 238: 688-692, 1987. 2. Szpirer C, Riviere M, Cortese R, Nakamura T, Islam MQ, Levan G, Szpirer J (June 1992). "Chromosomal localization in man and rat of the genes encoding the liver-enriched transcription factors C/EBP, DBP, and HNF1/LFB-1 (CEBP, DBP, and transcription factor 1, TCF1, respectively) and of the hepatocyte growth factor/scatter factor gene (HGF)". Genomics 13 (2): 293-300. 3. Vaxillaire M, Boccio V, Philippi A, Vigouroux C, Terwilliger J, Passa P, Beckmann JS, Velho G, Lathrop GM, Froguel P (April 1995). "A gene for maturity onset diabetes of the young (MODY) maps to chromosome 12q". Nat. Genet. 9 (4): 418-23. -
说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
-
: "Protocatechuic acid inhibits hepatitis B virus replication by activating ERK1/2 pathway and down-regulating HNF4α and HNF1α in vitro." in: Life sciences, Vol. 180, pp. 68-74, (2017) (PubMed).
-
: "Protocatechuic acid inhibits hepatitis B virus replication by activating ERK1/2 pathway and down-regulating HNF4α and HNF1α in vitro." in: Life sciences, Vol. 180, pp. 68-74, (2017) (PubMed).
-
- HNF1A (HNF1 Homeobox A (HNF1A))
-
别名
- HNF1A
-
背景
-
Synonyms: Hepatocyte nuclear factor 1-alpha,HNF-1-alpha,HNF-1A,Liver-specific transcription factor LF-B1,LFB1,Transcription factor 1,TCF-1,HNF1A,TCF1,
Tissue Specificity: Liver.
Background: HNF1 homeobox A (hepatocyte nuclear factor 1 homeobox A), also known as HNF1A or TCF1, is a human gene. It is mapped to chromosome 12q24.3. The protein encoded by this gene is a transcription factor that is highly expressed in the liver and is involved in the regulation of the expression of several liver-specific genes. HNF1A can function as a dimer. What's more, deletion of the HNF1A activation domains or interruption of the HNF1-binding sites in the LCT promoter resulted in complete loss of transcriptional activity.
Sequence Similarities: Belongs to the HNF1 homeobox family.
-
分子量
- 80 kDa
-
基因ID
- 6927
-
UniProt
- P20823
-
途径
- Hormone Transport, Carbohydrate Homeostasis
抗原
-
