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HNF1A 抗体 (AA 431-631)

Cited in 1 publication. This anti-HNF1A antibody is a 兔 多克隆 antibody detecting HNF1A in WB. Suitable for 人.
产品编号 ABIN3042451
发货至: 中国
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Quick Overview for HNF1A 抗体 (AA 431-631) (ABIN3042451)

抗原

See all HNF1A 抗体
HNF1A (HNF1 Homeobox A (HNF1A))

适用

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宿主

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克隆类型

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多克隆

标记

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This HNF1A antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 431-631

    原理

    Anti-HNF1/HNF1A Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-HNF1/HNF1A Antibody (ABIN3042451). Tested in WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human HNF1 recombinant protein (Position: A431-Q631). Human HNF1 shares 93% and 92% amino acid (aa) sequences identity with mouse and rat HNF1, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Dai, Cai, Wu, Chen, Han: "Protocatechuic acid inhibits hepatitis B virus replication by activating ERK1/2 pathway and down-regulating HNF4α and HNF1α in vitro." in: Life sciences, Vol. 180, pp. 68-74, (2017) (PubMed).

  • 抗原

    HNF1A (HNF1 Homeobox A (HNF1A))

    别名

    HNF1A

    背景

    Synonyms: Hepatocyte nuclear factor 1-alpha,HNF-1-alpha,HNF-1A,Liver-specific transcription factor LF-B1,LFB1,Transcription factor 1,TCF-1,HNF1A,TCF1,

    Tissue Specificity: Liver.

    Background: HNF1 homeobox A (hepatocyte nuclear factor 1 homeobox A), also known as HNF1A or TCF1, is a human gene. It is mapped to chromosome 12q24.3. The protein encoded by this gene is a transcription factor that is highly expressed in the liver and is involved in the regulation of the expression of several liver-specific genes. HNF1A can function as a dimer. What's more, deletion of the HNF1A activation domains or interruption of the HNF1-binding sites in the LCT promoter resulted in complete loss of transcriptional activity.

    Sequence Similarities: Belongs to the HNF1 homeobox family.

    分子量

    80 kDa

    基因ID

    6927

    UniProt

    P20823

    途径

    Hormone Transport, Carbohydrate Homeostasis
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