HDAC7 抗体 (N-Term)
Quick Overview for HDAC7 抗体 (N-Term) (ABIN3042441)
抗原
See all HDAC7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 68-103, N-Term
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原理
- Anti-HDAC7 Antibody Picoband®
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序列
- QLLHKDKSKR SAVASSVVKQ KLAEVILKKQ QAALER
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-HDAC7 Antibody Picoband® (ABIN3042441). Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human HDAC7, different from the related mouse and rat sequences by one amino acid.
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Rat
1. "Entrez Gene: HDAC7A histone deacetylase 7A". 2. Kao HY, Downes M, Ordentlich P, Evans RM (Jan 2000). "Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression". Genes & Development 14 (1): 55-66. 3. Marks PA, Richon VM, Rifkind RA (Aug 2000). "Histone deacetylase inhibitors: inducers of differentiation or apoptosis of transformed cells". Journal of the National Cancer Institute 92 (15): 1210-6. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- HDAC7 (Histone Deacetylase 7 (HDAC7))
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别名
- HDAC7
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背景
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Synonyms: Histone deacetylase 7,HD7,3.5.1.98,Histone deacetylase 7A,HD7a,HDAC7,HDAC7A,
Tissue Specificity: Liver.
Background: Histone deacetylase 7 is an enzyme that in humans is encoded by the HDAC7 gene. It is mapped to 12q13.1. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation / deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Sequence Similarities: Contains 1 HMG box DNA-binding domain.
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分子量
- 103 kDa
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基因ID
- 51564
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途径
- Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development
抗原
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