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GRK5 抗体 (C-Term)

GRK5 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3042434
发货至: 中国
  • 抗原 See all GRK5 抗体
    GRK5 (G Protein-Coupled Receptor Kinase 5 (GRK5))
    抗原表位
    • 8
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 393-429, C-Term
    适用
    • 38
    • 26
    • 16
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 36
    • 2
    • 1
    克隆类型
    • 37
    • 2
    多克隆
    标记
    • 22
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GRK5 antibody is un-conjugated
    应用范围
    • 23
    • 21
    • 18
    • 6
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    原理
    Anti-GRK5 Antibody Picoband®
    序列
    KREEVDRRVL ETEEVYSHKF SEEAKSICKM LLTKDAK
    交叉反应 (详细)
    No cross-reactivity with other proteins
    产品特性
    Anti-GRK5 Antibody Picoband® (ABIN3042434). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human GRK5, different from the related mouse and rat sequences by three amino acids.
    亚型
    IgG
    Top Product
    Discover our top product GRK5 Primary Antibody
  • 应用备注
    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
    1. "Entrez Gene: GRK5 G protein-coupled receptor kinase 5". 2. Bullrich F, Druck T, Kunapuli P, et al. (1995). "Chromosomal mapping of the genes GPRK5 and GPRK6 encoding G protein-coupled receptor kinases GRK5 and GRK6.". Cytogenet. Cell Genet. 70 (3-4): 250-4. 3. Kunapuli P, Benovic JL (Jul 1993). "Cloning and expression of GRK5: a member of the G protein-coupled receptor kinase family". Proc Natl Acad Sci U S A 90 (12): 5588-92.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原
    GRK5 (G Protein-Coupled Receptor Kinase 5 (GRK5))
    别名
    GRK5 (GRK5 产品)
    背景

    Synonyms: G protein-coupled receptor kinase 5,2.7.11.16,G protein-coupled receptor kinase GRK5,GRK5,GPRK5,

    Tissue Specificity: Highest levels in heart, placenta, lung > skeletal muscle > brain, liver, pancreas > kidney. .

    Background: G protein-coupled receptor kinase 5?is an?enzyme?that in humans is encoded by the?GRK5?gene. It is mapped to 10q26.11. This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs).

    分子量
    68 kDa
    基因ID
    2869
    UniProt
    P34947
    途径
    Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
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