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GRK5 抗体 (C-Term)

This anti-GRK5 antibody is a 兔 多克隆 antibody detecting GRK5 in WB 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN3042434
发货至: 中国

Quick Overview for GRK5 抗体 (C-Term) (ABIN3042434)

抗原

See all GRK5 抗体
GRK5 (G Protein-Coupled Receptor Kinase 5 (GRK5))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This GRK5 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 393-429, C-Term

    原理

    Anti-GRK5 Antibody Picoband®

    序列

    KREEVDRRVL ETEEVYSHKF SEEAKSICKM LLTKDAK

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-GRK5 Antibody Picoband® (ABIN3042434). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human GRK5, different from the related mouse and rat sequences by three amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
    1. "Entrez Gene: GRK5 G protein-coupled receptor kinase 5". 2. Bullrich F, Druck T, Kunapuli P, et al. (1995). "Chromosomal mapping of the genes GPRK5 and GPRK6 encoding G protein-coupled receptor kinases GRK5 and GRK6.". Cytogenet. Cell Genet. 70 (3-4): 250-4. 3. Kunapuli P, Benovic JL (Jul 1993). "Cloning and expression of GRK5: a member of the G protein-coupled receptor kinase family". Proc Natl Acad Sci U S A 90 (12): 5588-92.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    GRK5 (G Protein-Coupled Receptor Kinase 5 (GRK5))

    别名

    GRK5

    背景

    Synonyms: G protein-coupled receptor kinase 5,2.7.11.16,G protein-coupled receptor kinase GRK5,GRK5,GPRK5,

    Tissue Specificity: Highest levels in heart, placenta, lung > skeletal muscle > brain, liver, pancreas > kidney. .

    Background: G protein-coupled receptor kinase 5?is an?enzyme?that in humans is encoded by the?GRK5?gene. It is mapped to 10q26.11. This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs).

    分子量

    68 kDa

    基因ID

    2869

    UniProt

    P34947

    途径

    Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
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