GRIA4 抗体 (AA 176-350)
Quick Overview for GRIA4 抗体 (AA 176-350) (ABIN3042429)
抗原
See all GRIA4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 176-350
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原理
- Anti-Ionotropic Glutamate receptor 4/GRIA4 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-Ionotropic Glutamate receptor 4/GRIA4 Antibody Picoband® (ABIN3042429). Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human GRIA4 recombinant protein (Position: Q176-K350). Human GRIA4 shares 99% amino acid (aa) sequence identity with both mouse and rat GRIA4.
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL, Mouse, Rat, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. "Entrez Gene: GRIA4 glutamate receptor, ionotrophic, AMPA 4" 2. Sommer, B., Keinanen, K., Verdoorn, T. A., Wisden, W., Burnashev, N., Herb, A., Kohler, M., Takagi, T., Sakmann, B., Seeburg, P. H. Flip and flop: a cell-specific functional switch in glutamate-operated channels of the CNS. Science 249: 1580-1585, 1990. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))
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别名
- GRIA4
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背景
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Synonyms: Glutamate receptor 4,GluR-4,GluR4,AMPA-selective glutamate receptor 4,GluR-D,Glutamate receptor ionotropic, AMPA 4,GluA4,GRIA4,GLUR4,
Background: Glutamate receptor 4 also named GRIA4 or GLUR4, is a protein that in humans is encoded by the GRIA4 gene. It is mapped to 11q22.3. This gene is a member of a family of L-glutamate-gated ion channels that mediate fast synaptic excitatory neurotransmission. These channels are also responsive to the glutamate agonist, alpha-amino-3-hydroxy-5-methyl-4-isoxazolpropionate (AMPA). Some haplotypes of this gene show a positive association with schizophrenia. What's more, glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels.
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分子量
- 101 kDa
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基因ID
- 2893
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UniProt
- P48058
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途径
- PI3K-Akt Signaling
抗原
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