Glutamate Receptor 3 抗体 (AA 29-360)
Quick Overview for Glutamate Receptor 3 抗体 (AA 29-360) (ABIN3042428)
抗原
See all Glutamate Receptor 3 (GRIA3) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 29-360
-
原理
- Anti-Glutamate receptor 3/GRIA3 Antibody Picoband®
-
交叉反应 (详细)
- No cross-reactivity with other proteins
-
产品特性
- Anti-Glutamate receptor 3/GRIA3 Antibody Picoband® (ABIN3042428). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human GRIA3 recombinant protein (Position: G29-M360). Human GRIA3 shares 99% amino acid (aa) sequence identity with both mouse and rat GRIA3.
-
亚型
- IgG
-
-
-
-
应用备注
-
Western blot, 0.1-0.5 μg/mL, Mouse, Rat, Human
1. "Entrez Gene: GRIA3 glutamate receptor, ionotrophic, AMPA 3 2. Hirbec, Hélène, Perestenko Olga, Nishimune Atsushi, Meyer Guido, Nakanishi Shigetada, Henley Jeremy M, Dev Kumlesh K (May 2002). "The PDZ proteins PICK1, GRIP, and syntenin bind multiple glutamate receptor subtypes. Analysis of PDZ binding motifs". J. Biol. Chem. (United States) 277 (18): 15221-4. 3. McNamara JO, Eubanks JH, McPherson JD, Wasmuth JJ, Evans GA, Heinemann SF (Jul 1992). "Chromosomal localization of human glutamate receptor genes". J Neurosci 12 (7): 2555-62. -
说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))
-
别名
- GRIA3
-
背景
-
Synonyms: Glutamate receptor 3,GluR-3,AMPA-selective glutamate receptor 3,GluR-C,GluR-K3,Glutamate receptor ionotropic, AMPA 3,GluA3,GRIA3,GLUR3, GLURC,
Tissue Specificity: Widely expressed in brain.
Background: Glutamate receptor 3 is a protein that in humans is encoded by the GRIA3 gene. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. It is mapped to Xq25. Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists.
Sequence Similarities: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIA3 subfamily.
-
分子量
- 101 kDa
-
基因ID
- 2892
-
UniProt
- P42263
-
途径
- PI3K-Akt Signaling, cAMP Metabolic Process, Synaptic Membrane
抗原
-