GATA5 抗体 (AA 1-397)
Quick Overview for GATA5 抗体 (AA 1-397) (ABIN3042418)
抗原
See all GATA5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-397
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原理
- Anti-GATA5 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-GATA5 Antibody Picoband® (ABIN3042418). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human GATA5 recombinant protein (Position: M1-A397). Human GATA5 shares 75% amino acid (aa) sequence identity with mouse GATA5.
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
1. Gao, X., Sedgwick, T., Shi, Y.-B., Evans, T. Distinct functions are implicated for the GATA-4, -5, and -6 transcription factors in the regulation of intestine epithelial cell differentiation. Molec. Cell. Biol. 18: 2901-2911, 1998. 2. "Entrez Gene: GATA5 GATA binding protein 5" -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- GATA5 (GATA Binding Protein 5 (GATA5))
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别名
- GATA5
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背景
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Synonyms: Transcription factor GATA-5,GATA-binding factor 5,GATA5 ,
Tissue Specificity: T-cells and endothelial cells.
Background: Transcription factor GATA-5, also named GATAS or GATA5, is a protein that in humans is encoded by the GATA5 gene. It is mapped to 20q13.33. The protein encoded by this gene is a transcription factor that contains two GATA-type zinc fingers. The encoded protein is known to bind to hepatocyte nuclear factor-1alpha (HNF-1alpha), and this interaction is essential for cooperative activation of the intestinal lactase-phlorizin hydrolase promoter. In other organisms, similar proteins may be involved in the establishment of cardiac smooth muscle cell diversity. In addition, the expression of GATA5 increased in a human colon cancer cell line within 2 hours of exposure to sodium butyrate, which induces differentiation.
Sequence Similarities: Contains 2 GATA-type zinc fingers.
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分子量
- 50 kDa
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基因ID
- 140628
抗原
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