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Glucose-6-Phosphate Dehydrogenase 抗体 (AA 315-515)

G6PD 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3042413
发货至: 中国
  • 抗原 See all Glucose-6-Phosphate Dehydrogenase (G6PD) 抗体
    Glucose-6-Phosphate Dehydrogenase (G6PD)
    抗原表位
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    AA 315-515
    适用
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    人, 小鼠
    宿主
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    克隆类型
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    多克隆
    标记
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    This Glucose-6-Phosphate Dehydrogenase antibody is un-conjugated
    应用范围
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    Western Blotting (WB)
    原理
    Anti-Glucose 6 Phosphate Dehydrogenase/G6PD Antibody Picoband®
    交叉反应 (详细)
    No cross-reactivity with other proteins
    产品特性
    Anti-Glucose 6 Phosphate Dehydrogenase/G6PD Antibody Picoband® (ABIN3042413). Tested in WB applications. This antibody reacts with Human;Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human G6PD recombinant protein (Position: E315-L515). Human G6PD shares 95% and 96% amino acid (aa) sequences identity with mouse and rat G6PD, respectively.
    亚型
    IgG
    Top Product
    Discover our top product G6PD Primary Antibody
  • 应用备注
    Western blot, 0.1-0.5 μg/mL, Human, Mouse
    1. Aster J, Kumar V, Robbins SL, Abbas AK, Fausto N, Cotran RS (2010). Robbins and Cotran pathologic basis of disease. Saunders/Elsevier. pp. Kindle Locations 33340-33341. 2. Takizawa, T., Huang, I.-Y., Ikuta, T., Yoshida, A. Human glucose-6-phosphate dehydrogenase: primary structure and cDNA cloning. Proc. Nat. Acad. Sci. 83: 4157-4161, 1986.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Hu, Zhang, Tang, Su, Li, Chen, Zhang, Cai, Zhu: "Variant G6PD levels promote tumor cell proliferation or apoptosis via the STAT3/5 pathway in the human melanoma xenograft mouse model." in: BMC cancer, Vol. 13, Issue 1, pp. 251, (2014) (PubMed).

  • 抗原
    Glucose-6-Phosphate Dehydrogenase (G6PD)
    别名
    G6PD (G6PD 产品)
    背景

    Synonyms: Glucose-6-phosphate 1-dehydrogenase,G6PD,1.1.1.49,G6PD,

    Tissue Specificity: Isoform Long is found in lymphoblasts, granulocytes and sperm.

    Background: Glucose-6-phosphate dehydrogenase, also known as G6PD or G6PDH, is an enzyme that in humans is encoded by the G6PD gene. It is mapped to Xq28. G6PD plays a key role in the production of ribose 5-phosphate and the generation of NADPH in the hexose monophosphate pathway. Because this pathway is the only NADPH-generation process in mature red cells, which lack the citric adid cycle, a genetic deficiency of G6PD is often associated with adverse physiologic effects. It has been found that aldosterone decreased G6PD expression and activity, resulting in increased oxidant stress and decreased nitric oxide levels, similar to what is observed in G6PD-deficient endothelial cells.

    Sequence Similarities: Belongs to the glucose-6-phosphate dehydrogenase family.

    分子量
    59 kDa
    基因ID
    2539
    UniProt
    P11413
    途径
    Regulation of Systemic Arterial Blood Pressure by Hormones
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