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- 抗原 See all FOXO1 抗体
- FOXO1 (Forkhead Box O1 (FOXO1))
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抗原表位
- AA 456-655
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FOXO1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for Forkhead box protein O1(FOXO1) detection. Tested with WB in Human,Rat.
- 交叉反应 (详细)
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Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - 产品特性
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Rabbit IgG polyclonal antibody for Forkhead box protein O1(FOXO1) detection. Tested with WB in Human,Rat.
Gene Name: forkhead box O1
Protein Name: Forkhead box protein O1 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human FOXO1A recombinant protein (Position: N456-G655). Human FOXO1A shares 93% amino acid (aa) sequence identity with both mouse and rat FOXO1A.
- 亚型
- IgG
- Top Product
- Discover our top product FOXO1 Primary Antibody
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Human, The detection limit for FOXO1A is approximately 0.25 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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MiR-15a/b promote adipogenesis in porcine pre-adipocyte via repressing FoxO1." in: Acta biochimica et biophysica Sinica, Vol. 46, Issue 7, pp. 565-71, (2014) (PubMed).
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MiR-15a/b promote adipogenesis in porcine pre-adipocyte via repressing FoxO1." in: Acta biochimica et biophysica Sinica, Vol. 46, Issue 7, pp. 565-71, (2014) (PubMed).
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- 抗原
- FOXO1 (Forkhead Box O1 (FOXO1))
- 别名
- FOXO1 (FOXO1 产品)
- 背景
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Forkhead box protein O1, also known as FKHR or FOXO1A, is a protein that in humans is encoded by the FOXO1 gene. It is mapped to 13q14.11. This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. FOXO1 plays important roles in regulation of gluconeogenesis and glycogenolysis by insulin signaling, and is also central to the decision for a preadipocyte to commit to adipogenesis. This gene is primarily regulated through phosphorylation on multiple residues. Its transcriptional activity is dependent on its phosphorylation state. What's more, FOXO1 may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.
Synonyms: FKH 1 antibody|FKH1 antibody|FKHR antibody|Forkhead (Drosophila) homolog 1 (rhabdomyosarcoma) antibody|Forkhead box O1 antibody|Forkhead box protein O1 antibody|Forkhead box protein O1A antibody|Forkhead in rhabdomyosarcoma antibody|Forkhead, Drosophila, homolog of, in rhabdomyosarcoma antibody|FoxO transcription factor antibody|foxo1 antibody|FOXO1_HUMAN antibody|FOXO1A antibody|OTTHUMP00000018301 antibody - 基因ID
- 2308
- UniProt
- Q12778
- 途径
- PI3K-Akt Signaling, Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, CXCR4-mediated Signaling Events, BCR Signaling
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