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FOXM1 抗体 (AA 411-763)

The 兔 多克隆 anti-FOXM1 antibody (ABIN3042402) specifically detects FOXM1 in WB. The antibody is reactive with 人 samples.
产品编号 ABIN3042402
发货至: 中国
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Quick Overview for FOXM1 抗体 (AA 411-763) (ABIN3042402)

抗原

See all FOXM1 抗体
FOXM1 (Forkhead Box M1 (FOXM1))

适用

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宿主

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克隆类型

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多克隆

标记

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This FOXM1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 411-763

    原理

    Anti-FOXM1 Antibody

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human FOXM1 shares 75%,76% amino acid (aa) sequences identity with mouse,rat FOXM1,respectively.

    产品特性

    Anti-FOXM1 Antibody. Tested in WB applications. This antibody reacts with Human.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human FOXM1 recombinant protein (Position: A411-Q763). Human FOXM1 shares 75% and 76% amino acid (aa) sequences identity with mouse and rat FOXM1, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    FOXM1 (Forkhead Box M1 (FOXM1))

    别名

    FOXM1

    背景

    Background: Forkhead box protein M1, also called FOXM1, is a protein that in humans is encoded by the FOXM1 gene. It is mapped to 12p13.33. The protein encoded by this gene is a member of the FOX family of transcription factors. FOXM1 is known to play a key role in cell cycle progression where endogenous FOXM1 expression peaks at S and G2/M phases and also in the control of cell proliferation. FOXM1 gene is now known as a human proto-oncogene. Abnormal upregulation of FOXM1 is involved in the oncogenesis of basal cell carcinoma, the most common human cancer worldwide. It was hypothesized that FOXM1 induces cancer initiation through stem/progenitor cell expansion. What's more, FOXM1 has been shown to modulate the epigenome. It was found that overexpression of FOXM1 brain washes normal cells to adopt cancer-like epigenome.

    Gene Full Name: forkhead box M1

    Sequence Similarities: Contains 1 fork-head DNA-binding domain.

    分子量

    36 kDa

    基因ID

    2305

    UniProt

    Q08050

    途径

    Positive Regulation of Response to DNA Damage Stimulus
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