FMO1 抗体 (C-Term)
Quick Overview for FMO1 抗体 (C-Term) (ABIN3042396)
抗原
See all FMO1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 334-363, C-Term
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原理
- Anti-FMO1 Antibody Picoband®
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序列
- AFPFLDESVV KVEDGQASLY KYIFPAHLQK
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-FMO1 Antibody Picoband® (ABIN3042396). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human FMO1, different from the related mouse sequence by one amino acid, and from the related rat sequence by two amino acids.
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亚型
- IgG
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anti-Flavin Containing Monooxygenase 1 (FMO1) (AA 363-532) antibody
FMO1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Flavin Containing Monooxygenase 1 (FMO1) (AA 40-89) antibodyFMO1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Flavin Containing Monooxygenase 1 (FMO1) antibodyFMO1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Flavin Containing Monooxygenase 1 (FMO1) (AA 2-271) antibodyFMO1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Flavin Containing Monooxygenase 1 (FMO1) (N-Term) antibodyFMO1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. "Entrez Gene: FMO1 flavin containing monooxygenase 1". 2. Cashman JR (2004). "The implications of polymorphisms in mammalian flavin-containing monooxygenases in drug discovery and development".Drug Discov. Today 9 (13): 574-581. 3. Dolphin C, Shephard EA, Povey S et al. (1991). "Cloning, primary sequence, and chromosomal mapping of a human flavin-containing monooxygenase (FMO1)".J. Biol. Chem. 266 (19): 12379-85. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- FMO1 (Flavin Containing Monooxygenase 1 (FMO1))
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别名
- FMO1
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背景
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Synonyms: Dimethylaniline monooxygenase [N-oxide-forming] 1,1.14.13.8,Dimethylaniline oxidase 1,Fetal hepatic flavin-containing monooxygenase 1,FMO 1,FMO1,
Tissue Specificity: Expressed mainly in fetal liver, adult kidney and, to a lesser extent, the intestine.
Background: Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Several transcript variants encoding different isoforms have been found for this gene.
Sequence Similarities: Belongs to the FMO family.
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分子量
- 60 kDa
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基因ID
- 2326
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UniProt
- Q01740
抗原
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