MGST1 抗体 (N-Term)
Quick Overview for MGST1 抗体 (N-Term) (ABIN3042364)
抗原
See all MGST1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 42-75, N-Term
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原理
- Anti-Microsomal Glutathione S-transferase 1/MGST1 Antibody Picoband®
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序列
- KVFANPEDCV AFGKGENAKK YLRTDDRVER VRRA
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-Microsomal Glutathione S-transferase 1/MGST1 Antibody Picoband® (ABIN3042364). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human MGST1, different from the related mouse sequence by six amino acids, and from the related rat sequence by five amino acids.
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human1. Lee SH, DeJong J (1999). "Microsomal GST-I: genomic organization, expression, and alternative splicing of the human gene.". Biochim. Biophys. Acta 1446 (3): 389-96. 2. "Entrez Gene: MGST1 microsomal glutathione S-transferase 1". -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- MGST1 (Microsomal Glutathione S-Transferase 1 (MGST1))
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别名
- MGST1
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背景
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Synonyms: Microsomal glutathione S-transferase 1,Microsomal GST-1,2.5.1.18,Microsomal GST-I,MGST1,GST12, MGST,
Tissue Specificity: Highly expressed in liver.
Background: Microsomal glutathione S-transferase 1 is an enzyme that in humans is encoded by the MGST1 gene. The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, two of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. Other family members, demonstrating glutathione S-transferase and peroxidase activities, are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. This gene encodes a protein that catalyzes the conjugation of glutathione to electrophiles and the reduction of lipid hydroperoxides. This protein is localized to the endoplasmic reticulum and outer mitochondrial membrane where it is thought to protect these membranes from oxidative stress. Several transcript variants, some non-protein coding and some protein coding, have been found for this gene.
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分子量
- 15 kDa
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基因ID
- 4257
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UniProt
- P10620
抗原
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