CYR61 抗体 (AA 54-381)
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北京 101111
Quick Overview for CYR61 抗体 (AA 54-381) (ABIN3042351)
抗原
See all CYR61 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 54-381
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原理
- Anti-CCN1/CYR61 Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-CCN1/CYR61 Antibody (ABIN3042351). Tested in WB applications. This antibody reacts with Human, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CCN1 recombinant protein (Position: K54-D381). Human CCN1 shares 91.8% and 92.1% amino acid (aa) sequence identity with mouse and rat CCN1, respectively.
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亚型
- IgG
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anti-Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) (AA 178-381) antibody
CYR61 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) (AA 176-379) antibodyCYR61 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) (AA 251-379) antibodyCYR61 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) antibodyCYR61 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) (Center) antibodyCYR61 适用: 人, 大鼠 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) (AA 25-381) antibodyCYR61 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) (AA 143-174) antibodyCYR61 适用: 人 WB 宿主: 兔 Polyclonal RB53929 unconjugated
anti-Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) (AA 47-332) antibodyCYR61 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) antibodyCYR61 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) (AA 25-381) antibodyCYR61 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3C11 unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))
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别名
- CYR61
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背景
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Synonyms: Protein CYR61,CCN family member 1,Cysteine-rich angiogenic inducer 61,Insulin-like growth factor-binding protein 10,IBP-10,IGF-binding protein 10,IGFBP-10,Protein GIG1,CYR61,CCN1, GIG1, IGFBP10,
Tissue Specificity: Kidney.
Background: Cysteine-rich angiogenic inducer 61 (CYR61) or CCN family member 1 (CCN1), is a matricellular protein that in humans is encoded by the CYR61 gene. CYR61 is a secreted, extracellular matrix (ECM)-associated signaling protein of the CCN family (CCN intercellular signaling protein). And it is capable of regulating a broad range of cellular activities, including cell adhesion, migration, proliferation, differentiation, apoptosis, and senescence through interaction with cell surface integrin receptors and heparan sulfate proteoglycans. During embryonic development, CYR61 is critical for cardiac septal morphogenesis, blood vessel formation in placenta, and vascular integrity. In adulthood CYR61 plays important roles in inflammation and tissue repair, and is associated with diseases related to chronic inflammation, including rheumatoid arthritis, atherosclerosis, diabetes-related nephropathy and retinopathy, and many different forms of cancers.
Sequence Similarities: Belongs to the CCN family.
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分子量
- 42 kDa
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基因ID
- 3491
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UniProt
- O00622
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途径
- Positive Regulation of Endopeptidase Activity, Growth Factor Binding
抗原
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