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CYR61 抗体 (AA 54-381)

This anti-CYR61 antibody is a 兔多克隆 antibody detecting CYR61 in WB. Suitable for 人和大鼠.

Western Blotting (WB) image for anti-Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) (AA 54-381) antibody (ABIN3042351) (CYR61 抗体 (AA 54-381))

1 image

产品编号 ABIN3042351

发货至: 中国

Quick Overview for CYR61 抗体 (AA 54-381) (ABIN3042351)

抗原

See all CYR61 抗体

CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))

适用

61
36
24
2
2
1
1
1
1
1
1

人, 大鼠

宿主

兔

克隆类型

多克隆

标记

35
4
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1

This CYR61 antibody is un-conjugated

应用范围

46
25
18
17
14
4
3
2
1
1

Western Blotting (WB)

Discover our top product CYR61 Primary Antibody

抗原表位
9

6

3

3

2

1

1

1

1

1

1

1

1

1
AA 54-381

原理

Anti-CCN1/CYR61 Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-CCN1/CYR61 Antibody Picoband® (ABIN3042351). Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human CCN1 recombinant protein (Position: K54-D381). Human CCN1 shares 91.8% and 92.1% amino acid (aa) sequence identity with mouse and rat CCN1, respectively.

亚型

IgG
anti-Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) (AA 178-381) antibody
CYR61 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) (AA 176-379) antibody
CYR61 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) (AA 251-379) antibody
CYR61 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) antibody
CYR61 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) (Center) antibody
CYR61 适用: 人, 大鼠 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) (AA 25-381) antibody
CYR61 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) (AA 143-174) antibody
CYR61 适用: 人 WB 宿主: 兔 Polyclonal RB53929 unconjugated

anti-Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) (AA 47-332) antibody
CYR61 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) antibody
CYR61 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated

anti-Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) (AA 25-381) antibody
CYR61 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3C11 unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human, Rat
1. Lau LF (October 2011). "CCN1/CYR61: the very model of a modern matricellular protein". Cell. Mol. Life Sci. 68 (19): 3149-63. 2. Jay P, Berge-Lefranc JL, Marsollier C, Mejean C, Taviaux S, Berta P (May 1997). "The human growth factor-inducible immediate early gene, CYR61, maps to chromosome 1p". Oncogene 14 (14): 1753-7. 3. Jun JI, Lau LF (December 2011). "Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets". Nature Reviews Drug Discovery 10 (12): 945-63.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))

别名

CYR61

背景

Synonyms: Protein CYR61,CCN family member 1,Cysteine-rich angiogenic inducer 61,Insulin-like growth factor-binding protein 10,IBP-10,IGF-binding protein 10,IGFBP-10,Protein GIG1,CYR61,CCN1, GIG1, IGFBP10,
Tissue Specificity: Kidney.
Background: Cysteine-rich angiogenic inducer 61 (CYR61) or CCN family member 1 (CCN1), is a matricellular protein that in humans is encoded by the CYR61 gene. CYR61 is a secreted, extracellular matrix (ECM)-associated signaling protein of the CCN family (CCN intercellular signaling protein). And it is capable of regulating a broad range of cellular activities, including cell adhesion, migration, proliferation, differentiation, apoptosis, and senescence through interaction with cell surface integrin receptors and heparan sulfate proteoglycans. During embryonic development, CYR61 is critical for cardiac septal morphogenesis, blood vessel formation in placenta, and vascular integrity. In adulthood CYR61 plays important roles in inflammation and tissue repair, and is associated with diseases related to chronic inflammation, including rheumatoid arthritis, atherosclerosis, diabetes-related nephropathy and retinopathy, and many different forms of cancers.
Sequence Similarities: Belongs to the CCN family.

分子量

42 kDa

基因ID

3491

UniProt

O00622

途径

Positive Regulation of Endopeptidase Activity, Growth Factor Binding

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