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VWF 抗体 (AA 1304-1452)

Name: VWF 抗体 (AA 1304-1452)
SKU: ABIN3042349
Availability: OutOfStock

VWF 适用: 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

Anti- VWF Picoband antibody, IHC(P) IHC(P): Mouse Liver Tissue (VWF 抗体 (AA 1304-1452))

IHC

Western Blotting (WB) image for anti-Von Willebrand Factor (VWF) (AA 1304-1452) antibody (ABIN3042349) (VWF 抗体 (AA 1304-1452))

Anti- VWF Picoband antibody, Western blotting All lanes: Anti VWF at 0. (VWF 抗体 (AA 1304-1452))

3 images

(17 references)

产品编号 ABIN3042349

发货至: 中国

Datasheet as PDF

抗原 See all VWF 抗体

VWF (Von Willebrand Factor (VWF))
抗原表位
33

15

11

10

7

6

4

3

2

1

1

1

1

1

1

1

1

1

1

1

1
AA 1304-1452
适用
152

33

22

4

3

2

2

1
大鼠, 小鼠
宿主
83

76

13

7

1

1
兔
Compatible Secondaries
克隆类型
91

86

2
多克隆
标记
87

17

14

7

4

4

4

4

4

4

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This VWF antibody is un-conjugated
应用范围
97

88

76

58

49

42

25

19

15

14

14

9

7

6

6

5

5

4

3

3

3

3

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

原理

Anti-Von Willebrand Factor/VWF Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-Von Willebrand Factor/VWF Antibody Picoband® (ABIN3042349). Tested in IF, IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived mouse VWF recombinant protein (Position: M1304-E1452).

亚型

IgG

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应用备注

Western blot, 0.1-0.5 μg/mL, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat
Immunofluorescence, 2 μg/mL, Rat
1. Sadler JE (1998). "Biochemistry and genetics of von Willebrand factor". Annu. Rev. Biochem. 67: 395-424. 2. Ginsburg, D., Handin, R. I., Bonthron, D. T., Donlon, T. A., Bruns, G. A. P., Latt, S. A., Orkin, S. H. Human von Willebrand factor (VWF): isolation of complementary DNA (cDNA) clones and chromosomal localization. Science 228: 1401-1406, 1985. 3. Sporn, L. A., Marder, V. J., Wagner, D. D. Von Willebrand factor released from Weibel-Palade bodies binds more avidly to extracellular matrix than that secreted constitutively. Blood 69: 1531-1534, 1987.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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抗原

VWF (Von Willebrand Factor (VWF))

别名

VWF (VWF 产品)

背景

Synonyms: von Willebrand factor,vWF,von Willebrand antigen 2,von Willebrand antigen II,Vwf ,
Tissue Specificity: Plasma. Expressed in liver. .
Background: Von Willebrand factor (VWF) is a blood glycoprotein involved in hemostasis. It is mapped to 12p13.31. The VWF gene encodes von Willebrand factor (VWF), a large multimeric glycoprotein that plays a central role in the blood coagulation system, serving both as a major mediator of platelet-vessel wall interaction and platelet adhesion, and as a carrier for coagulation factor VIII. VWF released from endothelial cell Weibel-Palade bodies bound particularly avidly to the extracellular matrix. VWF deficiency or dysfunction (von Willebrand disease) leads to a bleeding tendency, which is most apparent in tissues having high blood flow shear in narrow vessels.
Sequence Similarities: Contains 1 CTCK (C-terminal cystine knot-like) domain.

分子量

309 kDa

基因ID

22371