BCL10 抗体 (AA 1-233)
Quick Overview for BCL10 抗体 (AA 1-233) (ABIN3042330)
抗原
See all BCL10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-233
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原理
- Anti-Bcl10 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Bcl10 Antibody Picoband® (ABIN3042330). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Bcl10 recombinant protein (Position: M1-Q233). Human Bcl10 shares 91% and 91.4% amino acid (aa) sequence identity with mouse and rat Bcl10, respectively.
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亚型
- IgG
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anti-B-Cell CLL/lymphoma 10 (BCL10) antibody
BCL10 适用: 人, 小鼠 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 4F8 unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) (AA 122-168) antibodyBCL10 适用: 人 IHC, IF, FACS, StM 宿主: 兔 Monoclonal BL10-2988R unconjugated Recombinant Antibody
anti-B-Cell CLL/lymphoma 10 (BCL10) (AA 122-168) antibodyBCL10 适用: 人 WB, IHC, FACS, StM 宿主: 小鼠 Monoclonal BL10-411 unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) antibodyBCL10 适用: 人, 犬 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 6A8 unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) (AA 98-234) antibodyBCL10 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3C11F4 unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) (AA 1-143) antibodyBCL10 适用: 人 WB, FACS, IHC (p) 宿主: 小鼠 Monoclonal 1185CT13-2-1-2 unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) antibodyBCL10 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) (AA 1-233) antibodyBCL10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) (AA 24-51), (N-Term) antibodyBCL10 适用: 人, 小鼠 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB24271 unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) antibodyBCL10 适用: 人, 小鼠 WB, IF, IHC (p), EIA 宿主: 小鼠 Monoclonal 4F8 unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
1. Ruland, J., Duncan, G. S., Elia, A., del Barco Barrantes, I., Nguyen, L., Plyte, S., Millar, D. G., Bouchard, D., Wakeham, A., Ohashi, P. S., Mak, T. W.Bcl10 is a positive regulator of antigen receptor-induced activation of NF-kappa-B and neural tube closure.Cell 104: 33-42, 2001. 2. Willis, T. G., Jadayel, D. M., Du, M.-Q., Peng, H., Perry, A. R., Abdul-Rauf, M., Price, H., Karran, L., Majekodunmi, O., Wlodarska, I., Pan, L., Crook, T., Hamoudi, R., Isaacson, P. G., Dyer, M. J. S.Bcl10 is involved in t(1,14)(p22,q32) of MALT B cell lymphoma and mutated in multiple tumor typesCell 96: 35-45, 1999. 3. Xue, L., Morris, S. W., Orihuela, C., Tuomanen, E., Cui, X., Wen, R., Wang, D.Defective development and function of Bcl10-deficient follicular, marginal zone and B1 B cells.Nature Immun. 4: 857-865, 2003. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- BCL10 (B-Cell CLL/lymphoma 10 (BCL10))
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别名
- BCL10
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背景
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Synonyms: B-cell lymphoma/leukemia 10,B-cell CLL/lymphoma 10,Bcl-10,CARD-containing molecule enhancing NF-kappa-B,CARD-like apoptotic protein,hCLAP,CED-3/ICH-1 prodomain homologous E10-like regulator,CIPER,Cellular homolog of vCARMEN,cCARMEN,Cellular-E10,c-E10,Mammalian CARD-containing adapter molecule E10,mE10,BCL10,CIPER, CLAP,
Tissue Specificity: Ubiquitous.
Background: BCL10, B-cell CLL/lymphoma 10, gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The BCL10 gene is mapped to chromosome 1p22. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. And this protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy.
Sequence Similarities: Contains 1 CARD domain.
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分子量
- 28 kDa
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基因ID
- 8915
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UniProt
- O95999
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
抗原
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