Butyrylcholinesterase 抗体 (AA 263-571)
Quick Overview for Butyrylcholinesterase 抗体 (AA 263-571) (ABIN3042329)
抗原
See all Butyrylcholinesterase (BCHE) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 263-571
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原理
- Anti-Butyrylcholinesterase/BCHE Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-Butyrylcholinesterase/BCHE Antibody Picoband® (ABIN3042329). Tested in WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived mouse BCHE recombinant protein (Position: K263-E571). Mouse BCHE shares 78% amino acid (aa) sequence identity with human BCHE.
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL, Mouse
1. Allderdice PW, Gardner HA, Galutira D, Lockridge O, LaDu BN, McAlpine PJ (Oct 1991). "The cloned butyrylcholinesterase (BCHE) gene maps to a single chromosome site, 3q26". Genomics 11 (2): 452-4. 2. Jasmin L (2013-05-28). "Cholinesterase - blood". University of Maryland Medical Center. 3. Pohanka M (2013). "Butyrylcholinesterase as a biochemical marker". Bratislavské Lekárske Listy 114 (12): 726-734. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Butyrylcholinesterase (BCHE)
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别名
- Bche
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背景
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Synonyms: Cholinesterase,3.1.1.8,Acylcholine acylhydrolase,Butyrylcholine esterase,Choline esterase II,Pseudocholinesterase,Bche,
Tissue Specificity: Present in most cells except erythrocytes.
Background: Butyrylcholinesterase (BCHE, or BuChE), also known as pseudocholinesterase or plasma cholinesterase, is a non-specific cholinesterase enzyme that hydrolyses many different choline esters. In humans, it is found primarily in the liver and is encoded by the BCHE gene. Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.
Sequence Similarities: Contains 1 CARD domain.
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分子量
- 85-90 kDa
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基因ID
- 12038
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UniProt
- Q03311
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途径
- Peptide Hormone Metabolism
抗原
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