VWF 抗体 (AA 2535-2813)
(16 references)Quick Overview for VWF 抗体 (AA 2535-2813) (ABIN3042328)
抗原
See all VWF 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2535-2813
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原理
- Anti-Von Willebrand Factor/VWF Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Von Willebrand Factor/VWF Antibody Picoband® (ABIN3042328). Tested in Flow Cytometry, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human VWF recombinant protein (Position: R2535-K2813). Human VWF shares 79% amino acid (aa) sequence identity with mouse VWF.
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亚型
- IgG
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anti-Von Willebrand Factor (VWF) (AA 1498-1665) antibody
VWF 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) (AA 269-367) antibodyVWF 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) (AA 1815-1939) antibodyVWF 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal VWF-1465 unconjugated
anti-Von Willebrand Factor (VWF) (AA 50-150) antibodyVWF 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) (AA 1304-1452) antibodyVWF 适用: 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) antibodyVWF 适用: 人 WB, IHC, FACS, ELISA 宿主: 小鼠 Monoclonal 907CT12-1-9 unconjugated
anti-Von Willebrand Factor (VWF) (AA 351-450) antibodyVWF 适用: 人, 大鼠, 小鼠 FACS, ICC, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) (AA 49-230) antibodyVWF 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) (AA 1815-1939) antibodyVWF 适用: 人 WB, IHC, StM 宿主: 兔 Monoclonal VWF-1859R unconjugated Recombinant Antibody
anti-Von Willebrand Factor (VWF) (AA 1815-1939) antibodyVWF 适用: 人 WB, IHC, IP, StM 宿主: 小鼠 Monoclonal rVWF-1465 unconjugated Recombinant Antibody
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL
Immunocytochemistry, 0.5-1 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x106 cells
1. Sadler JE (1998). "Biochemistry and genetics of von Willebrand factor". Annu. Rev. Biochem. 67: 395-424. 2. Ginsburg, D., Handin, R. I., Bonthron, D. T., Donlon, T. A., Bruns, G. A. P., Latt, S. A., Orkin, S. H. Human von Willebrand factor (VWF): isolation of complementary DNA (cDNA) clones and chromosomal localization. Science 228: 1401-1406, 1985. 3. Sporn, L. A., Marder, V. J., Wagner, D. D. Von Willebrand factor released from Weibel-Palade bodies binds more avidly to extracellular matrix than that secreted constitutively. Blood 69: 1531-1534, 1987. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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: "Expression and correlation analysis of RegIV and vascular endothelial growth factors (VEGF-A and VEGF-C) in metastatic spinal tumors." in: Oncology letters, Vol. 13, Issue 5, pp. 3517-3521, (2017) (PubMed).
: "Inhibition of angiogenesis by arsenic trioxide via TSP-1-TGF-β1-CTGF-VEGF functional module in rheumatoid arthritis." in: Oncotarget, Vol. 8, Issue 43, pp. 73529-73546, (2017) (PubMed).
: "Calcium signaling is implicated in the diffuse axonal injury of brain stem." in: International journal of clinical and experimental pathology, Vol. 8, Issue 5, pp. 4388-97, (2016) (PubMed).
: "Effect of Hyperbaric Oxygen on the Growth of Intracranial Glioma in Rats." in: Chinese medical journal, Vol. 128, Issue 23, pp. 3197-203, (2016) (PubMed).
: "Resveratrol Protects against TNF-α-Induced Injury in Human Umbilical Endothelial Cells through Promoting Sirtuin-1-Induced Repression of NF-KB and p38 MAPK." in: PLoS ONE, Vol. 11, Issue 1, pp. e0147034, (2016) (PubMed).
: "Paxillin regulates vascular endothelial growth factor A-induced in vitro angiogenesis of human umbilical vein endothelial cells." in: Molecular medicine reports, Vol. 11, Issue 3, pp. 1784-92, (2015) (PubMed).
: "Correction: IFI6 Inhibits Apoptosis via Mitochondrial-Dependent Pathway in Dengue Virus 2 Infected Vascular Endothelial Cells." in: PLoS ONE, Vol. 10, Issue 9, pp. e0138896, (2015) (PubMed).
: "Construction of tissue-engineered bone using a bioreactor and platelet-rich plasma." in: Experimental and therapeutic medicine, Vol. 8, Issue 2, pp. 413-418, (2014) (PubMed).
: "Effects of propranolol and isoproterenol on infantile hemangioma endothelial cells in vitro." in: Experimental and therapeutic medicine, Vol. 8, Issue 2, pp. 647-651, (2014) (PubMed).
: "Effects of transforming growth factor-?2 on myocilin expression and secretion in human primary cultured trabecular meshwork cells." in: International journal of clinical and experimental pathology, Vol. 7, Issue 8, pp. 4827-36, (2014) (PubMed).
: "Pinocembrin, a major flavonoid in propolis, improves the biological functions of EPCs derived from rat bone marrow through the PI3K-eNOS-NO signaling pathway." in: Cytotechnology, Vol. 65, Issue 4, pp. 541-51, (2013) (PubMed).
: "Performance of a multilayered small-diameter vascular scaffold dual-loaded with VEGF and PDGF." in: Biomaterials, Vol. 34, Issue 30, pp. 7302-13, (2013) (PubMed).
: "Vascularized bone tissue formation induced by fiber-reinforced scaffolds cultured with osteoblasts and endothelial cells." in: BioMed research international, Vol. 2013, pp. 854917, (2013) (PubMed).
: "Development of an optimized protocol for primary culture of smooth muscle cells from rat thoracic aortas." in: Cytotechnology, Vol. 61, Issue 1-2, pp. 65-72, (2010) (PubMed).
: "PlexinA1 expression in gastric carcinoma and its relationship with tumor angiogenesis and proliferation." in: World journal of gastroenterology, Vol. 13, Issue 48, pp. 6558-61, (2007) (PubMed).
: "Histological type of oncogenity and expression of cell cycle genes in tumor cells from human mesenchymal stem cells." in: Oncology reports, Vol. 16, Issue 5, pp. 1021-8, (2006) (PubMed).
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: "Expression and correlation analysis of RegIV and vascular endothelial growth factors (VEGF-A and VEGF-C) in metastatic spinal tumors." in: Oncology letters, Vol. 13, Issue 5, pp. 3517-3521, (2017) (PubMed).
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- VWF (Von Willebrand Factor (VWF))
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别名
- VWF
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背景
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Synonyms: von Willebrand factor,vWF,von Willebrand antigen 2,von Willebrand antigen II,VWF,F8VWF,
Tissue Specificity: Plasma.
Background: Von Willebrand factor (VWF) is a blood glycoprotein involved in hemostasis. It is mapped to 12p13.31. The VWF gene encodes von Willebrand factor (VWF), a large multimeric glycoprotein that plays a central role in the blood coagulation system, serving both as a major mediator of platelet-vessel wall interaction and platelet adhesion, and as a carrier for coagulation factor VIII. VWF released from endothelial cell Weibel-Palade bodies bound particularly avidly to the extracellular matrix. VWF deficiency or dysfunction (von Willebrand disease) leads to a bleeding tendency, which is most apparent in tissues having high blood flow shear in narrow vessels.
Sequence Similarities: Contains 1 CTCK (C-terminal cystine knot-like) domain.
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分子量
- 309 kDa
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基因ID
- 7450
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UniProt
- P04275
抗原
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