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CD33 抗体 (Biotin)

This anti-CD33 antibody is a 小鼠 单克隆 antibody detecting CD33 in FACS. Suitable for 人.
产品编号 ABIN303561
发货至: 中国

Quick Overview for CD33 抗体 (Biotin) (ABIN303561)

抗原

See all CD33 抗体
CD33

适用

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宿主

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小鼠

克隆类型

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  • 1
单克隆

标记

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This CD33 antibody is conjugated to Biotin

应用范围

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Flow Cytometry (FACS)

克隆位点

HIM3-4
  • 特异性

    The antibody HIM3-4 reacts with CD33, a 67 kDa type I transmembrane glycoprotein (immunoglobulin superfamily) expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells, it is absent on platelets, lymphocytes, erythrocytes and hematopoietic stem cells. HLDA V, WS Code M MA112. HLDA VI, WS Code M MA47.

    纯化方法

    Affinity Chromatography

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS, pH ~7.4, 15 mM Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原

    CD33

    别名

    CD33 / SIGLEC3

    背景

    CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies, these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia.Synonyms: Myeloid cell surface antigen CD33, Sialic acid-binding Ig-like lectin 3, Siglec-3, gp67

    基因ID

    945

    UniProt

    P20138
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