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CD38 抗体 (Biotin)

适用: 人 FACS 宿主: 小鼠 Monoclonal HIT2 Biotin
产品编号 ABIN303555
发货至: 中国
  • 抗原 See all CD38 抗体
    CD38
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD38 antibody is conjugated to Biotin
    应用范围
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    Flow Cytometry (FACS)
    特异性
    This antibody reacts with CD38 (T10), a 45 kDa type II transmembrane glycoprotein strongly expressed mainly on plasma cells and activated T and B lymphocytes, it is an antigenic marker of lymphoid cells.
    交叉反应 (详细)
    Species reactivity (tested):Human
    免疫原
    Human thymocytes in foetus
    克隆位点
    HIT2
    亚型
    IgG1
    Top Product
    Discover our top product CD38 Primary Antibody
  • 应用备注
    Flow Cytometry analysis: 1:500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原
    CD38
    Abstract
    CD38 产品
    背景
    CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation, proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid and lymphoid progenitor cells. Another role of CD38 is provided by enzymatic activity of its extracellular part. CD38 acts as NAD+ glycohydrolase converting NAD+ into ADP-ribose, as ADP-ribosyl cyclase producing cADPR and as cADPR hydrolase, thus affecting levels of calcium-mobilizing metabolites. ADPR produced by CD38 serves as an important second messenger of neutrophil and dendritic cell migration.Synonyms: ADP-ribosyl cyclase 1, Cyclic ADP-ribose hydrolase 1, T10, cADPr hydrolase 1
    基因ID
    952
    UniProt
    P28907
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