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Endoglin 抗体 (APC)

This anti-Endoglin antibody is a 小鼠 单克隆 antibody detecting Endoglin in FACS. Suitable for 人.
产品编号 ABIN303549
发货至: 中国

Quick Overview for Endoglin 抗体 (APC) (ABIN303549)

抗原

See all Endoglin (ENG) 抗体
Endoglin (ENG)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Endoglin antibody is conjugated to APC

应用范围

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Flow Cytometry (FACS)

克隆位点

MEM-226
  • 纯化方法

    Size-exclusion chromatography

    免疫原

    Recombinant Vaccinia virus containing the human CD105 cDNA

    亚型

    IgG2a
  • 应用备注

    Flow Cytometry analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10^6 cells in a suspension.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
    Shelf Life: one year from despatch.

    有效期

    12 months
  • 抗原

    Endoglin (ENG)

    别名

    CD105 / Endoglin

    背景

    CD105 (Endoglin) is a homodimeric transmembrane glycoprotein serving in presence of TGFbR-2 as a receptor for TGFb-1 and TGFb-3. CD105 is highly expressed on endothelial cells and promotes angiogenesis during wound healing, infarcts and in a wide range of tumours and its gene expression is stimulated by hypoxia. CD105 prevents apoptosis in hypoxic endothelial cells and also antagonises the inhibitory effects of TGFb-1 on vascular endothelial cell growth and migration. Normal cellular levels of CD105 are required for formation of new blood vessels.Synonyms: END, ENG, HHT1, ORW, ORW1

    UniProt

    P17813
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