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CD53 抗体 (PE)

This anti-CD53 antibody is a 小鼠 单克隆 antibody detecting CD53 in FACS. Suitable for 人.
产品编号 ABIN303518
发货至: 中国

Quick Overview for CD53 抗体 (PE) (ABIN303518)

抗原

See all CD53 抗体
CD53

适用

  • 67
  • 5
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宿主

  • 40
  • 29
小鼠

克隆类型

  • 42
  • 24
  • 3
单克隆

标记

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This CD53 antibody is conjugated to PE

应用范围

  • 44
  • 33
  • 25
  • 18
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  • 12
  • 9
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Flow Cytometry (FACS)

克隆位点

MEM-53
  • 纯化方法

    Size-exclusion chromatography

    免疫原

    Leukocytes of pacient suffering from a LGL-type leukemia

    亚型

    IgG1
  • 应用备注

    Flow Cytometry analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 10^6 cells in a suspension.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Dilute only prior to immediate use

    储存条件

    4 °C

    储存方法

    Store the antibody (undiluted) at 2-8 °C. DO NOT FREEZE! Freezing alkaline phosphatase conjugates will result in a substantial loss of enzymatic activity.
  • 抗原

    CD53

    别名

    CD53

    背景

    CD53 is a tetraspanin family transmembrane glycoprotein expressed in the lymphoid-myeloid lineage. This molecule has been reported to form complexes with other leukocyte surface proteins such as CD2, CD19, CD21, MHC II, VLA-4 or tetraspanins CD37, CD81 and CD82, thus probably modulating various signaling processes. CD53 is involved in radioresistancy of tumour cells and its triggering has anti-apoptotic effect. In thymus, CD53 is up-regulated in response to positive selection signals during T cell development, and is strongly expressed upon macrophage exposure to bacterial lipopolysaccharide, whereas stimulation of neutrophils results in down-regulation of CD53 expression.Synonyms: Cell surface glycoprotein CD53, Leukocyte surface antigen CD53, MOX44, TSPAN25, Tetraspanin-25

    基因ID

    963

    NCBI登录号

    NP_000551

    UniProt

    P19397
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