MOAP1 抗体 (Center)
Quick Overview for MOAP1 抗体 (Center) (ABIN303284)
抗原
See all MOAP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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特异性
- This antibody recognises MAP-1 Protein (MOAP1).
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纯化方法
- Immunoaffinity Chromatography.
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免疫原
- Synthetic Peptide corresponding to 15 amino acid peptide from near the center of human MAP-1.
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anti-Modulator of Apoptosis 1 (MOAP1) (AA 1-351) antibody
MOAP1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4A1 unconjugated
anti-Modulator of Apoptosis 1 (MOAP1) (AA 1-351) antibodyMOAP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Modulator of Apoptosis 1 (MOAP1) (AA 1-351) antibodyMOAP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Immunohistochemistry on Paraffin Sections (2.5 μg/mL). Western Blot (1 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- Phosphate Buffered Saline PBS containing 0.02 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C to -70 °C for longer. Dilute only prior to immediate use.
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- MOAP1 (Modulator of Apoptosis 1 (MOAP1))
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别名
- MOAP1
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背景
- Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. Members of the Bcl-2 family are known to be critical regulators of this process. These proteins are characterized by the presence of several conserved motifs termed Bcl-2 homology (BH) domains. A related protein termed MAP-1 has recently been identified. This protein contains a BH3-like domain and induces caspase-dependent apoptosis in mammalian cells when overexpressed. It forms homodimers and associates with Bcl-2 family members such as Bax, Bcl-2, and Bcl-XL in vitro and in vivo. It has been suggested that MAP-1 associates with the tumor suppressor RASSF1A following death receptor activation, allowing a conformational change in Bax that leads to cellular apoptosis.Synonyms: MAP-1, MAP1, Modulator of apoptosis 1
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基因ID
- 64112
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NCBI登录号
- NP_071434
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UniProt
- Q96BY2
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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