IL-31 抗体 (Center)
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北京 101111
Quick Overview for IL-31 抗体 (Center) (ABIN303271)
抗原
See all IL-31 (IL31) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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特异性
- This antibody reacts with Interleukin 31 (IL31).
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纯化方法
- Affinity Chromatography.
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免疫原
- Synthetic Peptide corresponding to 18 amino acid peptide from near the center of human IL-31.
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anti-Interleukin 31 (IL31) antibody
IL31 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 31 (IL31) (AA 13-40), (N-Term) antibodyIL31 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB22575 unconjugated
anti-Interleukin 31 (IL31) (AA 24-164) antibodyIL31 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 31 (IL31) (AA 31-130) antibodyIL31 适用: 人 ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 31 (IL31) (AA 21-120) antibodyIL31 适用: 小鼠 WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 31 (IL31) (AA 28-154) antibodyIL31 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 31 (IL31) (AA 19-49), (N-Term) antibodyIL31 适用: 人, 小鼠 WB, IHC (p), FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 31 (IL31) antibodyIL31 适用: 人, 小鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 31 (IL31) (AA 55-183) antibodyIL31 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal A3 unconjugated
anti-Interleukin 31 (IL31) (AA 24-164) antibodyIL31 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5G9 unconjugated
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应用备注
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Immunohistochemistry on Paraffin Sections (5 μg/mL). Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate Buffered Saline PBS containing 0.02 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer. Dilute only prior to immediate use.
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- IL-31 (IL31) (Interleukin 31 (IL31))
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别名
- Interleukin-31 / IL31
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背景
- Interleukin-31 (IL-31) is a recently discovered T-cell cytokine closely related to IL-6 type cytokines and is preferentially produced by T helper type 2 cells. IL-31 activity is mediated through the ligand-induced oligomerization of a dimeric receptor complex containing IL-31 receptor A and oncostatin M receptor. In response to IL-31 binding, these proteins activate the JAK/STAT and the AKT signaling pathways. RNA levels of IL-31 receptor A and oncostatin M receptor are induced in activated monocytes but are expressed constitutively in epithelial cells. IL-31, when overexpressed in transgenic mice, results in the development of pruritis, alopecia and skin lesions, and in humans may result in atopic dermatitis, suggesting that IL-31 may represent a novel target for antipruritic drug development.Synonyms: IL-31
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基因ID
- 386653
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NCBI登录号
- NP_001014358
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UniProt
- Q6EBC2
抗原
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