RAB3A 抗体 (AA 192-220)
Quick Overview for RAB3A 抗体 (AA 192-220) (ABIN3032423)
抗原
See all RAB3A 抗体适用
宿主
克隆类型
标记
应用范围
- 
    - 
                                            抗原表位
- AA 192-220
- 
                                            纯化方法
- Antigen affinity
- 
                                            免疫原
- Amino acids 192-220 (DTADPAVTGAKQGPQLSDQQVPPHQDCAC-human) were used as the immunogen for this Rab3A antibody.
- 
                                            亚型
- IgG
 
- 
                                            
- 
    
- 
    - 
                                            应用备注
- The stated application concentrations are suggested starting amounts. Titration of the Rab3A antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
- 
                                            限制
- 仅限研究用
 
- 
                                            
- 
    - 
                                            缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- 
                                            储存条件
- -20 °C
- 
                                            储存方法
- After reconstitution, the Rab3A antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
 
- 
                                            
- 
    - RAB3A (RAB3A, Member RAS Oncogene Family (RAB3A))
- 
                                            别名
- Rab3A
- 
                                            背景
- Ras-related protein Rab-3A is a protein that in humans is encoded by the RAB3A gene. Synapsin I stimulated the Rab3A cycle by increasing GTP binding, GTPase activity, and Rab3A recruitment to the synaptic vesicle membrane. Conversely, Rab3A inhibited Synapsin I binding to actin and Synapsin I-induced synaptic vesicle clustering. It has been found that the protein is necessary for both forms of synaptic plasticity, and it is also involved in calcium exocytosis in neurons. In addition to that, Rab3A has been found to regulate a late step in synaptic vesicle fusion.
- 
                                            基因ID
- 5864
- 
                                            途径
- Synaptic Membrane, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
 抗原
- 
                    
 
                                     
                                     
                                    