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PROC 抗体 (AA 446-461)

PROC 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3032367
发货至: 中国
  • 抗原 See all PROC 抗体
    PROC (Vitamin K-dependent protein C (PROC))
    抗原表位
    • 8
    • 7
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 446-461
    适用
    • 88
    • 12
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 68
    • 16
    • 8
    • 3
    • 2
    • 1
    • 1
    克隆类型
    • 71
    • 27
    • 1
    多克隆
    标记
    • 61
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This PROC antibody is un-conjugated
    应用范围
    • 60
    • 48
    • 31
    • 20
    • 15
    • 9
    • 8
    • 8
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Antigen affinity
    免疫原
    Amino acids 446-461 (HGHIRDKEAPQKSWAP) were used as the immunogen for this Protein C antibody.
    亚型
    IgG
    Top Product
    Discover our top product PROC Primary Antibody
  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the Protein C antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the Protein C antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    PROC (Vitamin K-dependent protein C (PROC))
    别名
    Protein C (PROC 产品)
    别名
    proc antibody, si:ch1073-188c16.3 antibody, zgc:63987 antibody, PROC antibody, APC antibody, PC antibody, PROC1 antibody, THPH3 antibody, THPH4 antibody, proc1 antibody, MGC64425 antibody, PA antibody, protein C, inactivator of coagulation factors Va and VIIIa antibody, protein C (inactivator of coagulation factors Va and VIIIa), a antibody, protein C (inactivator of coagulation factors Va and VIIIa) antibody, protein C, inactivator of coagulation factors Va and VIIIa S homeolog antibody, vitamin K-dependent protein C antibody, prosaposin antibody, protein C antibody, proline rich protein HaeIII subfamily 1 antibody, PROC antibody, proca antibody, proc.S antibody, proc antibody, CpipJ_CPIJ000393 antibody, CpipJ_CPIJ002754 antibody, CpipJ_CPIJ003717 antibody, CpipJ_CPIJ003718 antibody, CpipJ_CPIJ014440 antibody, CpipJ_CPIJ018032 antibody, CpipJ_CPIJ018737 antibody, PSAP antibody, Proc antibody, PRH1 antibody
    物质类
    Viral Protein
    背景
    Protein C (PROC), also called PC, is a zymogenic (inactive) protein, the activated form of which plays an important role in regulating blood clotting, inflammation, cell death and maintaining the permeability of blood vessel walls in humans and other animals. The PROC gene is mapped on 2q14.3. The PROC gene contains 8 exons and spans about 11 kb by Foster et al. The conversion of Protein C to a protease with anticoagulant function by thrombin requires as a cofactor thrombomodulin, an endothelial cell membrane protein. Riewald et al. demonstrated that activated Protein C uses the endothelial cell protein C receptor as a coreceptor for cleavage of protease-activated receptor-1 on endothelial cells. Faust et al. demonstrated that the endothelial pathways required for Protein C activation are impaired in severe meningococcal sepsis. They stated that improvement in the outcome of children with meningococcal sepsis who were treated with unactivated Protein C concentrates had been described in case reports and in one uncontrolled series.
    UniProt
    P04070
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