PROC 抗体 (AA 446-461)
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Quick Overview for PROC 抗体 (AA 446-461) (ABIN3032367)
抗原
See all PROC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 446-461
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纯化方法
- Antigen affinity
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免疫原
- Amino acids 446-461 (HGHIRDKEAPQKSWAP) were used as the immunogen for this Protein C antibody.
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亚型
- IgG
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anti-Vitamin K-dependent protein C (PROC) (AA 32-131) antibody
PROC 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3A10 unconjugated
anti-Vitamin K-dependent protein C (PROC) antibodyPROC 适用: 人 ELISA, IHC, IHC (p), IEP 宿主: 山羊 Polyclonal unconjugated
anti-Vitamin K-dependent protein C (PROC) (AA 446-461), (C-Term) antibodyPROC 适用: 人 WB, IHC, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Vitamin K-dependent protein C (PROC) (AA 1-236) antibodyPROC 适用: 人 WB, IHC, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Vitamin K-dependent protein C (PROC) antibodyPROC 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Vitamin K-dependent protein C (PROC) (Middle Region) antibodyPROC 适用: 人, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vitamin K-dependent protein C (PROC) (AA 197-436) antibodyPROC 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vitamin K-dependent protein C (PROC) (AA 17-166) antibodyPROC 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vitamin K-dependent protein C (PROC) (AA 288-409) antibodyPROC 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Vitamin K-dependent protein C (PROC) (Internal Region) antibodyPROC 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- The stated application concentrations are suggested starting amounts. Titration of the Protein C antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the Protein C antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- PROC (Vitamin K-dependent protein C (PROC))
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别名
- Protein C
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背景
- Protein C (PROC), also called PC, is a zymogenic (inactive) protein, the activated form of which plays an important role in regulating blood clotting, inflammation, cell death and maintaining the permeability of blood vessel walls in humans and other animals. The PROC gene is mapped on 2q14.3. The PROC gene contains 8 exons and spans about 11 kb by Foster et al. The conversion of Protein C to a protease with anticoagulant function by thrombin requires as a cofactor thrombomodulin, an endothelial cell membrane protein. Riewald et al. demonstrated that activated Protein C uses the endothelial cell protein C receptor as a coreceptor for cleavage of protease-activated receptor-1 on endothelial cells. Faust et al. demonstrated that the endothelial pathways required for Protein C activation are impaired in severe meningococcal sepsis. They stated that improvement in the outcome of children with meningococcal sepsis who were treated with unactivated Protein C concentrates had been described in case reports and in one uncontrolled series.
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UniProt
- P04070
抗原
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