我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

PROC 抗体 (AA 446-461)

Name: PROC 抗体 (AA 446-461)
SKU: ABIN3032367
Availability: OutOfStock

This anti-PROC antibody is a 兔多克隆 antibody detecting PROC in WB 和 IHC (p). Suitable for 人.

Western blot testing of Protein C antibody and Lane 1: Jurkat; 2: CEM; 3: SMMC-7721; 4: HeLa cell lysate. (PROC 抗体 (AA 446-461))

IHC-P: Protein C antibody testing of human breast cancer tissue (PROC 抗体 (AA 446-461))

IHC

Western blot testing of Protein C antibody and Lane 1: Jurkat (PROC 抗体 (AA 446-461))

3 images

产品编号 ABIN3032367

发货至: 中国

Quick Overview for PROC 抗体 (AA 446-461) (ABIN3032367)

抗原

See all PROC 抗体

PROC (Vitamin K-dependent protein C (PROC))

适用

人

宿主

兔

克隆类型

多克隆

标记

This PROC antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Discover our top product PROC Primary Antibody

抗原表位
7

5

3

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 446-461

纯化方法

Antigen affinity

免疫原

Amino acids 446-461 (HGHIRDKEAPQKSWAP) were used as the immunogen for this Protein C antibody.

亚型

IgG
anti-Vitamin K-dependent protein C (PROC) (AA 32-131) antibody
PROC 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3A10 unconjugated

anti-Vitamin K-dependent protein C (PROC) antibody
PROC 适用: 人 ELISA, IHC, IHC (p), IEP 宿主: 山羊 Polyclonal unconjugated

anti-Vitamin K-dependent protein C (PROC) (AA 446-461), (C-Term) antibody
PROC 适用: 人 WB, IHC, ICC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Vitamin K-dependent protein C (PROC) (AA 1-236) antibody
PROC 适用: 人 WB, IHC, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Vitamin K-dependent protein C (PROC) antibody
PROC 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Vitamin K-dependent protein C (PROC) (Middle Region) antibody
PROC 适用: 人, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Vitamin K-dependent protein C (PROC) antibody
PROC 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Vitamin K-dependent protein C (PROC) (AA 197-436) antibody
PROC 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Vitamin K-dependent protein C (PROC) (AA 17-166) antibody
PROC 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Vitamin K-dependent protein C (PROC) (AA 288-409) antibody
PROC 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

应用备注

The stated application concentrations are suggested starting amounts. Titration of the Protein C antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

限制

仅限研究用
缓冲液

0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

储存条件

-20 °C

储存方法

After reconstitution, the Protein C antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
抗原

PROC (Vitamin K-dependent protein C (PROC))

别名

Protein C

背景

Protein C (PROC), also called PC, is a zymogenic (inactive) protein, the activated form of which plays an important role in regulating blood clotting, inflammation, cell death and maintaining the permeability of blood vessel walls in humans and other animals. The PROC gene is mapped on 2q14.3. The PROC gene contains 8 exons and spans about 11 kb by Foster et al. The conversion of Protein C to a protease with anticoagulant function by thrombin requires as a cofactor thrombomodulin, an endothelial cell membrane protein. Riewald et al. demonstrated that activated Protein C uses the endothelial cell protein C receptor as a coreceptor for cleavage of protease-activated receptor-1 on endothelial cells. Faust et al. demonstrated that the endothelial pathways required for Protein C activation are impaired in severe meningococcal sepsis. They stated that improvement in the outcome of children with meningococcal sepsis who were treated with unactivated Protein C concentrates had been described in case reports and in one uncontrolled series.

UniProt

P04070