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Progesterone Receptor 抗体 (AA 595-933)

The 兔 多克隆 anti-Progesterone Receptor antibody is suitable to detect Progesterone Receptor in samples from 人 和 大鼠. It has been validated for WB 和 IHC (p).
产品编号 ABIN3032309
发货至: 中国
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Quick Overview for Progesterone Receptor 抗体 (AA 595-933) (ABIN3032309)

抗原

See all Progesterone Receptor (PGR) 抗体
Progesterone Receptor (PGR)

适用

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人, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Progesterone Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 595-933

    纯化方法

    Antigen affinity

    免疫原

    Human partial recombinant protein (AA 595-933) was used as the immunogen for this Progesterone Receptor antibody.

    亚型

    IgG
  • 应用备注

    The stated application concentrations are suggested starting amounts. Titration of the Progesterone Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the Progesterone Receptor antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    Progesterone Receptor (PGR)

    别名

    Progesterone Receptor

    背景

    The progesterone receptor (PR) is an intracellular steroid receptor that specially binds progesterone in humans. It is encoded by a single PGR gene residing on chromosome 11q22. The PR gene uses separate promoters and translational start sites to produce 2 isoforms, PRA and PRB, which are identical except for an additional 165 amino acids present only in the N terminus of PRB. It can be observed in human breast tissues. The proteins function as dimeric molecules in nuclei to regulate the transcription of target genes in a ligand-responsive manner.

    UniProt

    P06401

    途径

    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration
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