PLK2 抗体 (C-Term)
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Quick Overview for PLK2 抗体 (C-Term) (ABIN3032267)
抗原
See all PLK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- PLK2 Antibody / Polo-like kinase 2
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序列
- SSELKNRMEY ALNMLLQRCN
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纯化方法
- Antigen affinity
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免疫原
- An amino acid sequence from the C-terminus of human Polo-like kinase 2 (SSELKNRMEYALNMLLQRCN) was used as the immunogen for this PLK2 antibody.
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亚型
- IgG
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应用备注
- The stated application concentrations are suggested starting amounts. Titration of the PLK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the PLK2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PLK2 (Polo-Like Kinase 2 (PLK2))
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别名
- PLK2
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背景
- Polo-like kinase 2, also known as SNK, is an enzyme that in humans is encoded by the PLK2 gene. It is a member of the polo family of serine/threonine protein kinases that have a role in normal cell division. The International Radiation Hybrid Mapping Consortium mapped the gene to chromosome 5. Polo-like kinase 2 is involved in synaptic plasticity, centriole duplication and G1/S phase transition. This gene plays a key role in synaptic plasticity and memory by regulating the Ras and Rap protein signalin: required for overactivity-dependent spine remodeling by phosphorylating the Ras activator RASGRF1 and the Rap inhibitor SIPA1L1 leading to their degradation by the proteasome.
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UniProt
- Q9NYY3
抗原
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