PF4 抗体 (AA 85-101)
Our Local Distributor
北京 101111
Quick Overview for PF4 抗体 (AA 85-101) (ABIN3032246)
抗原
See all PF4 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 85-101
-
纯化方法
- Antigen affinity
-
免疫原
- Amino acids 85-101 (DLQAPLYKKIIKKLLES-human) were used as the immunogen for this CXCL4 antibody.
-
亚型
- IgG
-
-
-
-
应用备注
- The stated application concentrations are suggested starting points. Titration of the CXCL4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
-
限制
- 仅限研究用
-
-
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- -20 °C
-
储存方法
- After reconstitution, the CXCL4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
-
-
- PF4 (Platelet Factor 4 (PF4))
-
别名
- CXCL4
-
背景
- Chemokine (C-X-C motif) ligand 4, is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. It belongs to the CXC chemokine family. The gene contains 3 exons spanning approximately 1 kb. It is encoded on a 10-kb EcoRI fragment of genomic DNA. By in situ hybridization, the gene is mapped to chromosome 4q12-q21. CXCL4s major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, the cytokine probably has a role in inflammation and wound repair.
-
UniProt
- P02776
抗原
-