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PAK6 抗体 (N-Term)

This anti-PAK6 antibody is a 兔 多克隆 antibody detecting PAK6 in WB 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN3032121
发货至: 中国

Quick Overview for PAK6 抗体 (N-Term) (ABIN3032121)

抗原

See all PAK6 抗体
PAK6 (P21-Activated Kinase 6 (PAK6))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

  • 77
多克隆

标记

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This PAK6 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    N-Term

    纯化方法

    Antigen affinity

    免疫原

    An amino acid sequence from the N-terminus of human PAK6 (QNFQHRVHTSFDPKEGK) was used as the immunogen for this PAK6 antibody (100% homologous in human, mouse and rat).

    亚型

    IgG
  • 应用备注

    The stated application concentrations are suggested starting amounts. Titration of the PAK6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the PAK6 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    PAK6 (P21-Activated Kinase 6 (PAK6))

    别名

    PAK6

    背景

    P21 protein-activated kinase 6 is an enzyme that in humans is encoded by the PAK6 gene. This gene encodes a protein that shares a high degree of sequence similarity with p21-activated kinase (PAK) family members. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding(CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor(AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development. The p21-activated protein kinase 6 gene was found to be highly expressed in testis and prostate tissues and the encoded protein was shown to cotranslocate into the nucleus with AR in response to androgen.

    UniProt

    Q9NQU5
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