NRP2 抗体 (AA 45-60)
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Quick Overview for NRP2 抗体 (AA 45-60) (ABIN3031982)
抗原
See all NRP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 45-60
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纯化方法
- Antigen affinity
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免疫原
- Amino acids 45-60 (YPQDYPSHQNCEWIVY-human) were used as the immunogen for this NRP2 antibody (100% mouse homology).
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亚型
- IgG
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anti-Neuropilin 2 (NRP2) (AA 231-490) antibody
NRP2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neuropilin 2 (NRP2) (AA 150-420) antibodyNRP2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuropilin 2 (NRP2) antibodyNRP2 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuropilin 2 (NRP2) (AA 60-209) antibodyNRP2 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuropilin 2 (NRP2) (AA 747-758), (Extracellular) antibodyNRP2 适用: 人 WB, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Neuropilin 2 (NRP2) antibodyNRP2 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Neuropilin 2 (NRP2) (N-Term) antibodyNRP2 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Neuropilin 2 (NRP2) (AA 621-715) antibodyNRP2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B8 unconjugated
anti-Neuropilin 2 (NRP2) antibodyNRP2 适用: 人, 大鼠, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Neuropilin 2 (NRP2) (AA 621-715) antibodyNRP2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- The stated application concentrations are suggested starting amounts. Titration of the NRP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the NRP2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- NRP2 (Neuropilin 2 (NRP2))
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别名
- NRP2
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背景
- Neuropilin-2, also called Npn2 or VEGF165R2, is a member of the neuropilin family of receptor proteins. Sema3b can act to repulse axons expressing neuropilin-2 and can antagonize the repulsive action of Sema3a on axonal growth cones expressing neuropilin-1. NRP2 may play a role in cardiovascular development, axon guidance, and tumorigenesis. Mice with null mutations in genes encoding Sema3F, and its holoreceptor components NRP2 and Plexin A3 (PLEXA3) exhibit increased dentate gyrus granule cell and cortical layer V pyramidal neuron spine number and size, and also aberrant spine distribution. Moreover, Sema3F promotes loss of spines and excitatory synapses in dissociated neurons in vitro, and in NRP2-null brain slices cortical layer V and dentate gyrus granule cells exhibit increased miniature excitatory postsynaptic current frequency. These disparate effects of secreted semaphorins are reflected in the restricted dendritic localization of Neuropilin-2 to apical dendrites and of NRP1 to all dendrites of cortical pyramidal neurons.
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UniProt
- O60462
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途径
- Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
抗原
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