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Netrin 1 抗体 (AA 32-51)

NTN1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3031963
发货至: 中国
  • 抗原 See all Netrin 1 (NTN1) 抗体
    Netrin 1 (NTN1)
    抗原表位
    • 15
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 32-51
    适用
    • 46
    • 42
    • 34
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 55
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    克隆类型
    • 60
    • 9
    多克隆
    标记
    • 38
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Netrin 1 antibody is un-conjugated
    应用范围
    • 52
    • 22
    • 20
    • 13
    • 13
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    Western Blotting (WB)
    纯化方法
    Antigen affinity
    免疫原
    Amino acids 32-51 (AGQAAQPDPCSDENGHPRRC) were used as the immunogen for this Netrin 1 antibody (100% homologous in human, mouse and rat).
    亚型
    IgG
    Top Product
    Discover our top product NTN1 Primary Antibody
  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the Netrin 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the Netrin 1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    Netrin 1 (NTN1)
    别名
    Netrin 1 (NTN1 产品)
    别名
    ntn1-A antibody, Netrin-1 antibody, NTN1 antibody, unc-6 antibody, MGC147073 antibody, NTN1L antibody, AI561871 antibody, BC019633 antibody, netrin-1 antibody, netrin 1 L homeolog antibody, netrin 1 antibody, ntn1.L antibody, NTN1 antibody, ntn1 antibody, Ntn1 antibody
    背景
    Netrin-1 (NTN1), also known as NTN1L, is a diffusible protein made by floor plate cells. It is found in the floor plate and neuroepithelial cells of the ventral region of the spinal cord, as well as other locations in the nervous system including the somatic mesoderm, pancreas and cardiac muscle. The human NTN1 gene is mapped to chromosome 17p13-p12 by FISH. Netrin-1 can attract spinal commissural axons and repel trochlear axons in vitro. And expression confers a selective advantage for tumor cell survival. The binding of netrin-1 to DCC appears to depend on the presence of a coreceptor or accessory proteins. Adenosine A2b receptor is actually its receptor and induces cAMP accumulation on binding netrin-1, and that dependent outgrowth of dorsal spinal cord axons directly involves A2b. Netrin-1 can promote intestinal tumor development, probably by regulating cell survival. Thus, a receptor or receptors function as conditional tumor suppressors.
    UniProt
    O95631
    途径
    Regulation of Cell Size
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