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MPG 抗体 (C-Term)

This anti-MPG antibody is a 兔 多克隆 antibody detecting MPG in WB. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN3031925
发货至: 中国

Quick Overview for MPG 抗体 (C-Term) (ABIN3031925)

抗原

See all MPG 抗体
MPG (N-Methylpurine-DNA Glycosylase (MPG))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This MPG antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    纯化方法

    Antigen affinity

    免疫原

    An amino acid sequence from the C-terminus of human MPG (NKSFDQRDLAQDEAVW) was used as the immunogen for this MPG antibody.

    亚型

    IgG
  • 应用备注

    The stated application concentrations are suggested starting amounts. Titration of the MPG antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the MPG antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    MPG (N-Methylpurine-DNA Glycosylase (MPG))

    别名

    MPG

    背景

    N-Methylpurine-DNA glycosylase is encoded by the MPG gene, mapped to human chromosome 16 by analysis of a panel of DNAs from mouse/human and hamster/human hybrid cell lines. The gene was expressed in all cell lines and tissues examined, but was found at particularly high levels in a colon adenocarcinoma cell line (HT29). The completely characterized human gene was found to span 7 to 8 kb of genomic DNA and to be localized 75 kb upstream of the embryonic zeta-globin gene. To assess the contribution of MPG to the repair of several mutagenic lesions in vivo, Hang et al.(1997) biochemically analyzed cell-free extracts of tissues from mice with a targeted deletion of the gene. Following treatment with DNA-methylating agents, increased persistence of 7-methylguanine (meG) was found in liver sections of MPG knockout mice in comparison with wildtype mice, demonstrating an in vivo phenotype for the MPG-null animals.

    UniProt

    P29372

    途径

    DNA Damage Repair
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