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MFN2 抗体 (AA 601-757)

This anti-MFN2 antibody is a 兔 多克隆 antibody detecting MFN2 in WB. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN3031819
发货至: 中国

Quick Overview for MFN2 抗体 (AA 601-757) (ABIN3031819)

抗原

See all MFN2 抗体
MFN2 (Mitofusin 2 (MFN2))

适用

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人, 大鼠, 小鼠

宿主

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  • 2

克隆类型

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多克隆

标记

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This MFN2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 601-757

    纯化方法

    Antigen affinity

    免疫原

    Human partial recombinant protein (AA 601-757) was used as the immunogen for this MFN2 antibody.

    亚型

    IgG
  • 应用备注

    The stated application concentrations are suggested starting amounts. Titration of the MFN2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the MFN2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    MFN2 (Mitofusin 2 (MFN2))

    别名

    MFN2

    背景

    Mitofusin-2 is a protein that in humans is encoded by the MFN2 gene. It is mapped to chromosome 1 and encodes a 757-amino acid protein that contains an ATP/GTP-binding site motif. This gene is expressed in many tissues and cell lines such as brain and KG-1 with the highest expression in heart and skeletal muscle. It has been found that MFN2 triggers mitochondrial energization, at least in part, by regulating OXPHOS expression through signals that are independent of its role as a mitochondrial fusion protein. And it contributes to the maintenance and operation of the mitochondrial network. Axonal CMT type 2A and autosomal dominant HMSN VI are caused by MFN2 and mutations of, which emphasizes its important role of mitochondrial function for both optic atrophies and peripheral neuropathies.

    基因ID

    9927

    途径

    Skeletal Muscle Fiber Development
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