KIF2C 抗体 (AA 531-725)
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Quick Overview for KIF2C 抗体 (AA 531-725) (ABIN3031553)
抗原
See all KIF2C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 531-725
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纯化方法
- Antigen affinity
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免疫原
- Human partial recombinant protein (AA 531-725) was used as the immunogen for this MCAK antibody.
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亚型
- IgG
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应用备注
- The stated application concentrations are suggested starting amounts. Titration of the MCAK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the MCAK antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- KIF2C (Kinesin Family Member 2C (KIF2C))
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别名
- MCAK
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背景
- Kinesin-like protein, also called Mitotic centromere associated kinesin (MCAK), is a protein that in humans is encoded by the KIF2C gene. It is mapped to 1p34.1. The protein encoded by this gene is a member of kinesin-like protein family. Most proteins of this family are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein acts to regulate microtubule dynamics in cells and is important for anaphase chromosome segregation and may be required to coordinate the onset of sister centromere separation. MCAK uses microtubule depolymerizing activity to correct improper microtubule attachments at kinetochores.
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基因ID
- 11004
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途径
- Microtubule Dynamics
抗原
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