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KRT8 抗体 (N-Term)

This anti-KRT8 antibody is a 兔 多克隆 antibody detecting KRT8 in WB 和 IHC (p). Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN3031541
发货至: 中国

Quick Overview for KRT8 抗体 (N-Term) (ABIN3031541)

抗原

See all KRT8 抗体
KRT8 (Keratin 8 (KRT8))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This KRT8 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    N-Term

    纯化方法

    Antigen affinity

    免疫原

    An amino acid sequence from the N-terminus of human Cytokeratin 8 (QQQKTARSNMDNMFESYIN) was used as the immunogen for this Cytokeratin 8 antibody.

    亚型

    IgG
  • 应用备注

    The stated application concentrations are suggested starting amounts. Titration of the Cytokeratin 8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the Cytokeratin 8 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    KRT8 (Keratin 8 (KRT8))

    别名

    Cytokeratin 8

    背景

    Cytokeratin 8(CK8), also known as Keratin 8(K8), is a type II keratin. Among the various intermediate filament(IF) proteins, cytokeratin 8(CK8) is especially remarkable as it is produced early in embryogenesis, is the only type-II CK occurring in many simple epithelial cells, and can also be synthesized in certain non-epithelial cells. Cytokeratin 8 mRNA was abundant in fetal small intestine, placenta, pancreas, lung, liver, and kidney. Levels of cytokeratin 8 mRNA in placenta increased slightly during pregnancy. He et al.(2002) presented evidence that K8 is a new cytoplasmic target for JNK in Fas receptor-mediated signaling. The functional significance of this phosphorylation could relate to regulation of JNK signaling and/or regulation of keratin dynamics.

    UniProt

    P05787
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