HSD17B2 抗体 (AA 373-387)
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Quick Overview for HSD17B2 抗体 (AA 373-387) (ABIN3031272)
抗原
See all HSD17B2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 373-387
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纯化方法
- Antigen affinity
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免疫原
- Amino acids 373-387 (MPRALRMPNYKKKAT-human) were used as the immunogen for this HSD17B2 antibody.
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亚型
- IgG
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anti-Hydroxysteroid (17-Beta) Dehydrogenase 2 (HSD17B2) (AA 118-387) antibody
HSD17B2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 2 (HSD17B2) (AA 1-387) antibodyHSD17B2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 2 (HSD17B2) antibodyHSD17B2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 2 (HSD17B2) (C-Term) antibodyHSD17B2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 2 (HSD17B2) (AA 118-387) antibodyHSD17B2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 2 (HSD17B2) (AA 1-387) antibodyHSD17B2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 2 (HSD17B2) (AA 265-294) antibodyHSD17B2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB26219 unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 2 (HSD17B2) antibodyHSD17B2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 2 (HSD17B2) (AA 151-250) antibodyHSD17B2 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 2 (HSD17B2) antibodyHSD17B2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- The stated application concentrations are suggested starting amounts. Titration of the HSD17B2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the HSD17B2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- HSD17B2 (Hydroxysteroid (17-Beta) Dehydrogenase 2 (HSD17B2))
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别名
- HSD17B2
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背景
- HSD17B2(17-beta-hydroxysteroid dehydrogenase II), also called 17-beta-HSD II, is an enzyme with 387 amino acids, a predicted molecular weight of 42,782D, and associate with the membranes of the endoplasmic reticulum. The type 2 enzyme is capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. HSD17B2 mRNA was detected in 18 of 42 (43 % ) adenomas but not in prolactinomas. In the human endometrium, inactivation of 17-beta-estradiol to estrone is catalyzed by HSD17B2. And it activity distinguishing between disease-free and diseased endometria. It efficiently catalyzes the oxidative metabolism of androgens and estrogens, and it is expressed in a large series of human peripheral tissues. The previous paradigm that HSD17B2 activity in the endometrium is elevated during the secretory phase is confined to diseased endometrium but not to disease-free endometrium.
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UniProt
- P37059
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途径
- Steroid Hormone Biosynthesis
抗原
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