HSD17B10 抗体 (AA 48-261)
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Quick Overview for HSD17B10 抗体 (AA 48-261) (ABIN3031271)
抗原
See all HSD17B10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 48-261
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纯化方法
- Antigen affinity
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免疫原
- Human partial recombinant protein (AA 48-261) was used as the immunogen for this ERAB antibody.
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亚型
- IgG
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应用备注
- The stated application concentrations are suggested starting amounts. Titration of the ERAB antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,ICC: 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the ERAB antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))
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别名
- ERAB
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背景
- ERAB is also known as HSD17B10 or HADH2. This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. ERAB is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids and steroids, and is a subunit of mitochondrial ribonuclease P, which is involved in tRNA maturation. The protein has been implicated in the development of Alzheimer disease, and mutations in the gene are the cause of 17beta-hydroxysteroid dehydrogenase type 10 (HSD10) deficiency. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.
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基因ID
- 3028
抗原
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