HPN
适用: 人
WB, IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 555
应用备注
The stated application concentrations are suggested starting amounts. Titration of the Hepsin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
限制
仅限研究用
缓冲液
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
储存条件
-20 °C
储存方法
After reconstitution, the Hepsin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
抗原
Hepsin (HPN)
别名
Hepsin
背景
Hepsin, also known as TMPRSS1, is an enzyme that in humans is encoded by the HPN gene. Tsuji et al.(1991) mapped the gene to 19q11-q13.2. Using cDNA microarrays, Dhanasekaran et al.(2001) examined gene expression profiles of more than 50 normal and neoplastic prostate specimens and 3 common prostate cancer cell lines. Signature expression profiles of normal adjacent prostate, benign prostatic hypertrophy, localized prostate cancer, and metastatic, hormone-refractory prostate cancer were determined. In 3 different human cell lines, Guipponi et al.(2008) found that Hepsin was stably anchored in the endoplasmic reticulum.