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HAVCR1 抗体 (AA 289-307)

This anti-HAVCR1 antibody is a 兔 多克隆 antibody detecting HAVCR1 in WB, IHC (p) 和 IHC (fro). Suitable for 人 和 大鼠.
产品编号 ABIN3031182
发货至: 中国

Quick Overview for HAVCR1 抗体 (AA 289-307) (ABIN3031182)

抗原

See all HAVCR1 抗体
HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))

适用

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人, 大鼠

宿主

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克隆类型

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多克隆

标记

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This HAVCR1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 289-307

    纯化方法

    Antigen affinity

    免疫原

    Amino acids 289-307 (HPRAEDNIYIIEDRSRGAE-rat) were used as the immunogen for this TIM-1 antibody.

    亚型

    IgG
  • 应用备注

    Titration of the TIM-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    The lyophilized TIM-1 antibody can be stored at 4°C to -20°C. After reconstitution, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))

    别名

    TIM-1 (KIM-1)

    物质类

    Virus

    背景

    T-cell immunoglobulin and mucin domain-containing protein 1 (TIM-1) or Kidney injury molecule 1 (KIM-1), also known as HAVCR1 and HAVCR, is a protein that in humans is encoded by the KIM1 gene. Biochemical, mutational, and cell adhesion analyses confirm that TIM-1 is capable of homophilic interactions. The features identified in murine TIM1 is conserved in human protein. The protein is a receptor for virus through the infection of canine osteogenic sarcoma cells expressing HAVCR1 with HAV. Using a monoclonal antibody to mouse TIM-1, expression was seen after activation of naive T cells and on T cells differentiated in Th2-polarizing conditions. Ectopic expression during mouse T-cell differentiation leads to production of the Th2-type cytokine IL4, but not the Th1-type cytokine Ifng.

    UniProt

    O54947
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