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HSP70 抗体 (AA 577-596)

This anti-HSP70 antibody is a 兔 多克隆 antibody detecting HSP70 in WB, ICC, IHC (p) 和 IHC (fro). Suitable for 人 和 大鼠.
产品编号 ABIN3031162
发货至: 中国

Quick Overview for HSP70 抗体 (AA 577-596) (ABIN3031162)

抗原

See all HSP70 抗体
HSP70 (Heat Shock Protein 70 (HSP70))

适用

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人, 大鼠

宿主

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克隆类型

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多克隆

标记

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This HSP70 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 577-596

    纯化方法

    Antigen affinity

    免疫原

    Amino acids 577-596 (VISWLDANTLAEKDEFEHKR-human) were used as the immunogen for this HSP70 antibody.

    亚型

    IgG
  • 应用备注

    The stated application concentrations are suggested starting points. Titration of the HSP70 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the HSP70 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    HSP70 (Heat Shock Protein 70 (HSP70))

    别名

    HSP70

    背景

    HSPA1 (heat shock 70 kDa protein 1A) also known as HSPA1A, HSP72 or HSP70I, is a protein that in humans is encoded by the HSPA1A gene. This intronless gene encodes a 70 kDa heat shock protein which is a member of the heat shock protein 70 family. The HSPA1A gene encodes a predicted 641-amino acid protein. Shimizu et al.(1999) found that peripheral blood mononuclear cells of 18 major depression patients expressed a short HSPA1A transcript that utilized exon 1 rather than exon 2, which is found in the more common HSPA1A transcript. No protein was associated with expression of this short HSPA1A mRNA, possibly due to lack of a TATA box or loss of internal ribosome binding sites. Treatment with BGP-15, a pharmacologic inducer of HSP72 that can protect against obesity-induced insulin resistance, improved muscular architecture, strength, and contractile function in severely affected diaphragm muscles in mdx dystrophic mice.

    UniProt

    P08107
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