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HSPH1 抗体 (AA 713-733)

This anti-HSPH1 antibody is a 兔 多克隆 antibody detecting HSPH1 in WB, IHC (p) 和 IHC (fro). Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN3031140
发货至: 中国

Quick Overview for HSPH1 抗体 (AA 713-733) (ABIN3031140)

抗原

See all HSPH1 抗体
HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))

适用

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人, 大鼠, 小鼠

宿主

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  • 9
  • 1

克隆类型

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多克隆

标记

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This HSPH1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 11
    • 8
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    AA 713-733

    纯化方法

    Antigen affinity

    免疫原

    Amino acids 713-733 (EVMEWMNNVMNAQAKKSLDQD-human) were used as the immunogen for this HSP105 antibody.

    亚型

    IgG
  • 应用备注

    The stated application concentrations are suggested starting amounts. Titration of the HSP105 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the Hsp105 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))

    别名

    HSP105

    背景

    Heat shock protein 105, also called HSPH1 or HSP110, is a protein that in humans is encoded by the HSPH1 gene. Immunohistochemical analysis localizes HSP105 mainly in the cytoplasm. Database analysis indicates that both HSP105 isoforms are highly conserved during evolution. By analysis of radiation hybrids and human/rodent hybrid cell lines, the HSPH1 gene is mapped to chromosome 13. Both HSP105alpha and HSP105beta are upregulated in HeLa cells exposed to heat shock. HSP105alpha, but not HSP105beta, is also upregulate in response to other cell stresses. Following heat shock, HSP105 relocalizes from a cytoplasmic to perinuclear position. Additionally, it may constitute a major determinant for both prognosis and treatment response in colorectal cancer.

    UniProt

    Q92598
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