GRIA4 抗体 (AA 176-350)
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Quick Overview for GRIA4 抗体 (AA 176-350) (ABIN3031063)
抗原
See all GRIA4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 176-350
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纯化方法
- Antigen affinity
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免疫原
- Human partial recombinant protein (AA 176-350) was used as the immunogen for this GLUR4 antibody.
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亚型
- IgG
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应用备注
- The stated application concentrations are suggested starting amounts. Titration of the GLUR4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the GLUR4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))
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别名
- GLUR4 (Glutamate Receptor 4)
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背景
- Glutamate receptor 4 also named GRIA4 or GLUR4, is a protein that in humans is encoded by the GRIA4 gene. It is mapped to 11q22.3. This gene is a member of a family of L-glutamate-gated ion channels that mediate fast synaptic excitatory neurotransmission. These channels are also responsive to the glutamate agonist, alpha-amino-3-hydroxy-5-methyl-4-isoxazolpropionate (AMPA). Some haplotypes of this gene show a positive association with schizophrenia. Additionally, glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels.
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基因ID
- 2893
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途径
- PI3K-Akt Signaling
抗原
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